Contribution of aspiration to the diagnosis of lung cancer in endobronchial ultrasound-guided fine-needle biopsy

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dc.authoridYalçınsoy, Murat/0000-0003-3407-7359
dc.authoridARSLAN, Ahmet Kadir/0000-0001-8626-9542
dc.authoridAKATLI, AYSE NUR/0000-0002-9677-2456
dc.authorwosidYalçınsoy, Murat/ABI-1421-2020
dc.authorwosidARSLAN, Ahmet Kadir/AAA-2409-2020
dc.authorwosidAKATLI, AYSE NUR/ABH-4455-2020
dc.contributor.authorGuven, Arzu Nakis
dc.contributor.authorYalcinsoy, Murat
dc.contributor.authorAkatli, Ayse Nur
dc.contributor.authorArslan, Ahmet Kadir
dc.date.accessioned2024-08-04T20:50:56Z
dc.date.available2024-08-04T20:50:56Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVE: Endobronchial ultrasound-guided transbronchial needle aspiration has been successfully applied in both diagnosis and staging of mediastinal and hilar lymphadenopathies and masses, especially in malignant cases. However, the optimal procedure of Endobronchial ultrasound-guided transbronchial needle aspiration to further increase diagnostic yield and minimize processing complexity remains controversial. This study aims to compare aspiration biopsy (Endobronchial ultrasound-guided transbronchial needle aspiration) and non-aspiration biopsy (Endobronchial ultrasound-guided transbronchial needle capillary sampling) in terms of sample adequacy, diagnosis, and quality in malignant cases. METHODS: Between March 2018 and June 2020, Endobronchial ultrasound- guided was performed sequentially on patients with mediastinal and/or hilar lymph nodes that were considered malignant. Each lymphadenopathy was sampled with and without aspiration. A single-blinded pathologist evaluated the samples. RESULTS: A total of 84 lymph nodes evaluations of 51 patients were included. Most samples were taken from the right lower paratracheal lymph nodes ( n=27, 32.2%) and subcarinal LN (n=21, 25%). The mean size of the lymph nodes was 21.21 +/- 8.257 (8-40) mm. The agreement between the two procedures in terms of sample adequacy and diagnostic yield was 69.1% (95%CI 58-78.7, p=0.076). In addition, according to the goodness-of-fit statistics, the kappa values were 0.255 (p=0.015) and 0.302 (p=0.004) for sample adequacy and diagnostic yield, respectively. There was no difference between the two procedures in relation to complications. CONCLUSION: Although the agreement between the two procedures is weak, Endobronchial ultrasound-guided transbronchial needle capillary sampling can be performed with less personnel, without reducing diagnostic yield and tissue adequacy. These findings can assist clinicians in determining the optimal procedure for Endobronchial ultrasound-guided.en_US
dc.description.sponsorshipBAP unit of Inonu University [2015/45]en_US
dc.description.sponsorshipThis study was financially supported by the BAP unit of Inonu University (2015/45).en_US
dc.identifier.doi10.1590/1806-9282.20210759
dc.identifier.endpage1838en_US
dc.identifier.issn1806-9282
dc.identifier.issue12en_US
dc.identifier.pmid34909958en_US
dc.identifier.scopus2-s2.0-85121500816en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1832en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.20210759
dc.identifier.urihttps://hdl.handle.net/11616/100373
dc.identifier.volume67en_US
dc.identifier.wosWOS:000756351300018en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLung canceren_US
dc.subjectFine needle biopsyen_US
dc.subjectBronchoscopyen_US
dc.subjectLymph node biopsyen_US
dc.subjectsentinelen_US
dc.titleContribution of aspiration to the diagnosis of lung cancer in endobronchial ultrasound-guided fine-needle biopsyen_US
dc.typeArticleen_US

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