Beneficial effects of apricot-feeding on myocardial ischemia-reperfusion injury in rats

Basit Öğe Kaydı
dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authoridParlakpınar, Hakan/0000-0001-9497-3468
dc.authoridAcet, Ahmet/0000-0003-1131-1878
dc.authoridParlakpinar, Hakan/0000-0001-9497-3468
dc.authoridGül, Mehmet/0000-0002-1374-0783
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.authorwosidOzturk, Feral/A-2678-2016
dc.authorwosidParlakpınar, Hakan/T-6517-2018
dc.authorwosidAcet, Ahmet/AAB-3273-2021
dc.authorwosidParlakpinar, Hakan/V-6637-2019
dc.authorwosidGül, Mehmet/ABI-6336-2020
dc.contributor.authorParlakpinar, Hakan
dc.contributor.authorOlmez, Ercument
dc.contributor.authorAcet, Ahmet
dc.contributor.authorOzturk, Feral
dc.contributor.authorTasdemir, Seda
dc.contributor.authorAtes, Burhan
dc.contributor.authorGul, Mehmet
dc.date.accessioned2024-08-04T20:31:08Z
dc.date.available2024-08-04T20:31:08Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe present study was undertaken to evaluate the cardio-protective potential of apricot-feeding in the ischemia-reperfusion (I/R) model of rats in vivo. Rats were divided into three groups of 12 rats each. Group 1 was fed with a standard rat chow, groups 2 and 3 were fed with a standard rat chow supplemented with 10% or 20% dried apricot during 3 months before the beginning of I/R studies. To produce I/R, the left main coronary artery was occluded for 30 min, followed by 120 min reperfusion, in anesthetized rats. Infarct sizes were found significantly decreased in 10% (55.0 +/- 4.3%) and 20% (57.0 +/- 2.9%) apricot-fed groups compared to control group (68.7 +/- 2.0%). Light and electron microscopic evaluations of hearts also demonstrated similar beneficial effects on I/R injury in apricot-fed both groups. Total phenolic contents, DPPH radical scavenging and ferric-reducing power as in vitro antioxidant capacities of rat chows were significantly increased after supplementation with apricot for each ratio. Cu, Zn Superoxide dismutase (Cu, Zn SOD) and catalase (CAT) activities were increased, and lipid peroxidation was decreased significantly in the hearts of 20% apricot-fed group after I/R. In conclusion, we clearly demonstrated in vivo cardio-protective activity of apricot-feeding related to its antioxidant phenolic contents in rats subjected to myocardial I/R. (C) 2009 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipApricot Research Foundation of Malatya Governorshipen_US
dc.description.sponsorshipThis study was supported by Apricot Research Foundation of Malatya Governorship. The apricot used in this study was obtained from Karapinar Kirlangic; Koyleri Tarimsal Kalkinma Kooperatifi Akcadag/Malatya/TURKEY.en_US
dc.identifier.doi10.1016/j.fct.2009.01.014
dc.identifier.endpage808en_US
dc.identifier.issn0278-6915
dc.identifier.issn1873-6351
dc.identifier.issue4en_US
dc.identifier.pmid19271314en_US
dc.identifier.scopus2-s2.0-60849116117en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage802en_US
dc.identifier.urihttps://doi.org/10.1016/j.fct.2009.01.014
dc.identifier.urihttps://hdl.handle.net/11616/94756
dc.identifier.volume47en_US
dc.identifier.wosWOS:000264623000020en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofFood and Chemical Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApricoten_US
dc.subjectHearten_US
dc.subjectIschemia-reperfusion injuryen_US
dc.subjectRaten_US
dc.subjectNutritional antioxidantsen_US
dc.titleBeneficial effects of apricot-feeding on myocardial ischemia-reperfusion injury in ratsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu