Perinatal and neonatal outcomes of women with very early preterm premature rupture of membranes treated via serial transabdominal amnioinfusion and expectant management: Experience of a tertiary referral center in Turkey

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dc.authoridMELEKOGLU, RAUF/0000-0001-7113-6691
dc.authoridCelik, ebru/0000-0002-0774-4294
dc.authorwosidMELEKOGLU, RAUF/AAF-1614-2019
dc.authorwosidCelik, ebru/X-4343-2019
dc.contributor.authorMelekoglu, Rauf
dc.contributor.authorCelik, Ebru
dc.date.accessioned2024-08-04T20:51:57Z
dc.date.available2024-08-04T20:51:57Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim We compared the outcomes of serial transabdominal amnioinfusion and expectant management on the perinatal and neonatal outcomes of pregnancies complicated with very early preterm premature rupture of membranes (PPROM). Methods We retrospectively reviewed the records of patients with very early PPROM admitted to the University of Inonu School of Medicine from 2014 to 2019. All such patients received comprehensive counseling on the possible prognoses; all were offered pregnancy termination, expectant management, and serial transabdominal infusion. Results Sixty-three women met the inclusion criteria; 36 were assigned to the expectant management group and 27 were assigned to the amnioinfusion group. The median delivery latency and the gestational age at delivery were significantly higher in the amnioinfusion than the expectant management group [35 (11-90), 14 (7-48), p < 0.001; 27.6 (22.1-34.0), 22.3 (19.0-26.5), p < 0.001, respectively]. Serial transabdominal amnioinfusion was associated with significantly less neonatal mortality than expectant management (29.6 vs 83.3%, p < 0.001). Multivariate binary logistic regression showed that the odds of neonatal mortality were 6.12 times higher among neonates in the expectant management group compared to that of the serial transabdominal amnioinfusion group after adjusting for potential confounders. Severe neonatal morbidities were significantly more common in the expectant management group than in the amnioinfusion group (p = 0.011). Conclusion The present study has demonstrated a significant positive effect of serial transabdominal amnioinfusion procedure on latency period and neonatal morbidity and mortality in pregnant women complicated with very early PPROM.en_US
dc.identifier.doi10.1111/jog.15290
dc.identifier.endpage1739en_US
dc.identifier.issn1341-8076
dc.identifier.issn1447-0756
dc.identifier.issue7en_US
dc.identifier.pmid35598894en_US
dc.identifier.scopus2-s2.0-85130500760en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1732en_US
dc.identifier.urihttps://doi.org/10.1111/jog.15290
dc.identifier.urihttps://hdl.handle.net/11616/100664
dc.identifier.volume48en_US
dc.identifier.wosWOS:000798529500001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Obstetrics and Gynaecology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectamnioinfusionen_US
dc.subjectamniotic fluiden_US
dc.subjectexpectant managementen_US
dc.subjectpregnancy outcomesen_US
dc.subjectpreterm premature rupture of fetal membranesen_US
dc.titlePerinatal and neonatal outcomes of women with very early preterm premature rupture of membranes treated via serial transabdominal amnioinfusion and expectant management: Experience of a tertiary referral center in Turkeyen_US
dc.typeArticleen_US

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