A simple laboratory measurement for discrimination of transudative and exudative pleural effusion: Pleural viscosity

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dc.authoridKAYA, AKIN/0000-0003-1645-7761;
dc.authorwosidKAYA, AKIN/AAP-7682-2020
dc.authorwosidKAYA, AKIN/AAF-8545-2020
dc.authorwosidÇiledağ, Aydın/AAQ-4533-2020
dc.contributor.authorYetkin, O
dc.contributor.authorTek, I
dc.contributor.authorKaya, A
dc.contributor.authorCiledag, A
dc.contributor.authorNumanoglu, N
dc.date.accessioned2024-08-04T20:15:27Z
dc.date.available2024-08-04T20:15:27Z
dc.date.issued2006
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: The initial step in establishing the cause of an effusion is to determine whether the fluid is a transudate or exudate. Plasma viscosity is influenced by the concentration of plasma proteins and lipoproteins with the major contribution resulting from fibrinogen. In this study we aimed to evaluate the role of pleural fluid viscosity in discrimination of transudate and exudates. Materials and Methods: We studied prospectively 63 consecutive patients with pleural effusion in whom diagnostic or therapeutic thoracentesis had been performed. The criteria of Light were applied to differentiate transudates from exudates: 33 patients (23 mate, 13 female, mean age 68 +/- 4 years) had exudates and 30 patients (17 mate, 13 female, mean age = 68 +/- 5) had transudates (due to congestive heart failure). Measurements of pleural fluid and plasma viscosity were performed using a viscometer. Results: There was no statistically significant difference between patients with transudate and exudates in respect to plasma viscosity. However, pleural viscosities of the patients with exudates were significantly higher than those of patients with transudate (1.37 +/- 0.16 mPa vs 0.93 +/- 0.03 m Pa s p < 0.001, respectively). Pleural viscosity has a high sensitivity, specificity (94%, 93%, respectively), positive and negative predictive value (97%, 97%, respectively) for the discrimination of transudative or exudatetive pleural fluid. Conclusion: We have demonstrated for the first time that pleural viscosity of the exudative effusion is higher than that of transudative effusion with high sensitivity, specificity, positive and negative predictive value. Regarding the simplicity of this measurement, it may play a valuable role in the accurate and fast discrimination of pleural fluid. (c) 2005 Elsevier Ltd. Alt rights reserved.en_US
dc.identifier.doi10.1016/j.rmed.2005.10.010
dc.identifier.endpage1290en_US
dc.identifier.issn0954-6111
dc.identifier.issue7en_US
dc.identifier.pmid16305823en_US
dc.identifier.scopus2-s2.0-33646903685en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1286en_US
dc.identifier.urihttps://doi.org/10.1016/j.rmed.2005.10.010
dc.identifier.urihttps://hdl.handle.net/11616/94392
dc.identifier.volume100en_US
dc.identifier.wosWOS:000238639500021en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co Ltden_US
dc.relation.ispartofRespiratory Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectplasma viscosityen_US
dc.subjectpleural viscosityen_US
dc.subjectpleural effusionen_US
dc.subjecttransudateen_US
dc.subjectexudateen_US
dc.titleA simple laboratory measurement for discrimination of transudative and exudative pleural effusion: Pleural viscosityen_US
dc.typeArticleen_US

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