Effects of sodium selenite on some biochemical and hematological parameters of rainbow trout (Oncorhynchus mykiss Walbaum, 1792) exposed to Pb2+ and Cu2+

dc.authoridYılmaz, İsmet/0000-0002-7204-1050
dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authoridDurmaz, Gökhan/0000-0003-3423-8108
dc.authorwosidYılmaz, ismet/AAG-8946-2019
dc.authorwosidYılmaz, İsmet/P-9976-2015
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.authorwosidDurmaz, Gökhan/E-7121-2016
dc.contributor.authorAtes, Burhan
dc.contributor.authorOrun, Ibrahim
dc.contributor.authorTalas, Zeliha Selamoglu
dc.contributor.authorDurmaz, Gokhan
dc.contributor.authorYilmaz, Ismet
dc.date.accessioned2024-08-04T20:30:42Z
dc.date.available2024-08-04T20:30:42Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study was carried out to understand the preventive effect of selenium (Se4+) on heavy metal stress induced by lead and copper in rainbow trout (Oncorhynchus mykiss). Variation in glutathione peroxidase (Se-GSH-Px) and superoxide dismutase (SOD) activity, and in malondialdehyde (MDA) levels in liver, spleen, heart, and brain tissues of rainbow trout after 72 h of exposure to Pb2+ and Cu2+ were investigated in the presence and absence of Se4+. In the presence of Se4+, Se-GSH-Px activity and SOD activity were found to be higher and MDA levels were lower compared with in its absence. Hematological parameters were also determined and it has been observed that total leukocyte count (WBC), mean cell volume (MCV), and mean cell hemoglobin (MCH) were increased and erythrocyte number (RBC), hemoglobin (Hb), and hematocrit value (Hct; P < 0.05) were decreased in fish exposed to heavy metals in the absence of selenium. Selenium presence recovered hematological parameters to normal levels. In the light of our findings, it could be stated that Pb2+ and Cu2+ lead to dramatic changes in biochemical and hematological parameters and selenium caused these parameters to converge to control levels when it was administered concurrently with these heavy metals.en_US
dc.identifier.doi10.1007/s10695-007-9146-5
dc.identifier.endpage59en_US
dc.identifier.issn0920-1742
dc.identifier.issn1573-5168
dc.identifier.issue1en_US
dc.identifier.pmid18649023en_US
dc.identifier.scopus2-s2.0-40249103479en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage53en_US
dc.identifier.urihttps://doi.org/10.1007/s10695-007-9146-5
dc.identifier.urihttps://hdl.handle.net/11616/94471
dc.identifier.volume34en_US
dc.identifier.wosWOS:000253527500007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofFish Physiology and Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHeavy metalsen_US
dc.subjectSodium selenite (Se4+)en_US
dc.subjectRainbow trouten_US
dc.subjectOxidative stressen_US
dc.subjectHematological parametersen_US
dc.titleEffects of sodium selenite on some biochemical and hematological parameters of rainbow trout (Oncorhynchus mykiss Walbaum, 1792) exposed to Pb2+ and Cu2+en_US
dc.typeArticleen_US

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