P50 sensory gating in patients with vaginismus

dc.authoridozcan, abdulcemal/0000-0002-6759-7556
dc.authoridKarlıdağ, Rifat/0000-0002-3650-0774
dc.authorwosidozcan, abdulcemal/B-1348-2008
dc.authorwosidkarlıdağ, rıfat/AAB-4255-2021
dc.authorwosidKarlıdağ, Rifat/AAB-4281-2021
dc.contributor.authorGul, Isil Gogcegoz
dc.contributor.authorKarlidag, Rifat
dc.contributor.authorOzcan, A. Cemal
dc.date.accessioned2024-08-04T20:40:04Z
dc.date.available2024-08-04T20:40:04Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: P50 sensory gating was investigated in patients with primary vaginismus (PV) with the hypothesis that interpreting coping capacities as a stress factor during sexual intercourse by perceiving unrelated stimuli and an impairment of the sensory information processing may be associated with fear/anxiety related to a possible pain in vulvovagina. Methods: A total of 35 patients who were diagnosed with PV and 29 healthy volunteers matched for age and gender underwent P50 recording in the neurophysiology laboratory and the results were compared. Results: The PV group's P50 gating ratio and S1 amplitude were statistically significantly lower than in the control group. Conclusion: Sensory gating is required for filtering the stimuli coming to the brain and developing an appropriate behavioral response. The reduced formation of an appropriate behavioral response in the PV group can lead to a perception of excessive and unrelated stimuli coming from internal and external environments and interpreting these as a stress factor exceeding the capacity to cope. Our study is the first to evaluate sensory gating in PV patients and new studies with larger patient groups are required.en_US
dc.identifier.doi10.5455/apd.173179
dc.identifier.endpage269en_US
dc.identifier.issn1302-6631
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84923001187en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage264en_US
dc.identifier.urihttps://doi.org/10.5455/apd.173179
dc.identifier.urihttps://hdl.handle.net/11616/96687
dc.identifier.volume16en_US
dc.identifier.wosWOS:000349324400006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherCumhuriyet Univ Tip Fak Psikiyatri Anabilim Dalien_US
dc.relation.ispartofAnadolu Psikiyatri Dergisi-Anatolian Journal of Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectvaginismusen_US
dc.subjectsensory gatingen_US
dc.subjectp50en_US
dc.subjectneurophysiologyen_US
dc.subjectsexual functionen_US
dc.titleP50 sensory gating in patients with vaginismusen_US
dc.typeArticleen_US

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