Bioactive properties of powdered peppermint and spearmint extracts: Inhibition of key enzymes linked to hypertension and type 2 diabetes

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dc.authoridAhhmed, Abdulatef/0000-0001-6686-0271
dc.authoridCam, Mustafa/0000-0003-1258-0834
dc.authoridYilmaztekin, Murat/0000-0002-5667-9169
dc.authoridTELCİ, İsa/0000-0002-3651-1641
dc.authoridKonca, Yusuf/0000-0002-6231-1512
dc.authoridBAŞYİĞİT, Bülent/0000-0002-6617-1836
dc.authoridAlasalvar, Hamza/0000-0003-3000-7310
dc.authorwosidAhhmed, Abdulatef/GLS-8228-2022
dc.authorwosidCam, Mustafa/H-8035-2019
dc.authorwosidYilmaztekin, Murat/N-9692-2013
dc.authorwosidTELCİ, İsa/AAI-6920-2021
dc.authorwosidKonca, Yusuf/JVZ-2238-2024
dc.authorwosidBaşyiğit, Bülent/I-8797-2018
dc.authorwosidBAŞYİĞİT, Bülent/ABE-2570-2020
dc.contributor.authorCam, Mustafa
dc.contributor.authorBasyigit, Bulent
dc.contributor.authorAlasalvar, Hamza
dc.contributor.authorYilmaztekin, Murat
dc.contributor.authorAhhmed, Abdulatef
dc.contributor.authorSagdic, Osman
dc.contributor.authorKonca, Yusuf
dc.date.accessioned2024-08-04T20:47:13Z
dc.date.available2024-08-04T20:47:13Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPeppermint and spearmint, both members of the Lamiaceae family, have been used in the form of extracts, infusions, and decoctions, because of their health benefits. Consumers are looking for functional food products which not only provide health benefits but also necessitate less preparation time. Therefore, this study aimed to investigate the bioactive properties of powdered peppermint and spearmint extracts. Peppermint and spearmint extracts obtained using pressurized water extraction were made into powder forms with a spray dryer using the air inlet temperature of 140 degrees C. Powdered peppermint extract (PPE) and powdered spearmint extract (PSE) showed significant inhibition against key enzymes of type 2 diabetes (alpha-glucosidase) and hypertension (angiotensin 1-converting enzyme, ACE). Alpha glucosidase inhibition degree of PPE and PSE as IC50 values was 0.6 and 1.2 mg/mL, respectively, while IC50 values for the ACE inhibition test were 4.5 mg for PPE and 5.8 mg for PSE. The HPLC-DAD method for ACE inhibition activity showed the suitability of this method for plant extracts high in phenolics which had no interference effects on the results. There were no differences between PPE and PSE in the DPPH test. However, PPE had higher Trolox equivalent antioxidant capacity (190 mg/g) with the ABTS test than PSE (170 mg/g). The predominant phenolics of PPE and PSE were found to be eriocitrin (47 mg/g) and rosmarinic acid (27 mg/g), respectively.en_US
dc.description.sponsorshipScientific and Research Council of Turkey (TUBITAK) [113O471]en_US
dc.description.sponsorshipThis work was financially supported by the Scientific and Research Council of Turkey (TUBITAK) under the Project Number of 113O471.en_US
dc.identifier.doi10.1016/j.fbio.2020.100577
dc.identifier.issn2212-4292
dc.identifier.issn2212-4306
dc.identifier.scopus2-s2.0-85082629524en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.fbio.2020.100577
dc.identifier.urihttps://hdl.handle.net/11616/99239
dc.identifier.volume35en_US
dc.identifier.wosWOS:000535177600025en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofFood Bioscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMentha piperitaen_US
dc.subjectMentha spicataen_US
dc.subjectAlpha-glucosidaseen_US
dc.subjectAngiotensin 1-converting enzymeen_US
dc.subjectEriocitrinen_US
dc.subjectRosmarinic aciden_US
dc.titleBioactive properties of powdered peppermint and spearmint extracts: Inhibition of key enzymes linked to hypertension and type 2 diabetesen_US
dc.typeArticleen_US

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