The effect of advanced maternal age on perinatal outcomes in nulliparous singleton pregnancies

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dc.authoridKahveci, Bekir/0000-0002-8729-1669
dc.authoridÇetin, Cihan/0000-0001-9625-4328
dc.authoridMELEKOGLU, RAUF/0000-0001-7113-6691
dc.authoridÇetin, Cihan/0000-0001-9625-4328
dc.authorwosidKahveci, Bekir/GRX-4938-2022
dc.authorwosidÇetin, Cihan/P-8356-2017
dc.authorwosidMELEKOGLU, RAUF/AAF-1614-2019
dc.authorwosidÇetin, Cihan/GXF-7563-2022
dc.contributor.authorKahveci, Bekir
dc.contributor.authorMelekoglu, Rauf
dc.contributor.authorEvruke, Ismail Cuneyt
dc.contributor.authorCetin, Cihan
dc.date.accessioned2024-08-04T20:45:23Z
dc.date.available2024-08-04T20:45:23Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Pregnancy at advanced maternal age has become more common in both developed and developing countries over the last decades. The association between adverse perinatal outcomes and advanced maternal age has been a matter of controversy in several studies. The objective of this study is to investigate the impact of advanced maternal age on perinatal and neonatal outcomes of nulliparous singleton pregnancies. Methods: Records of patients admitted to the Department of Obstetrics and Gynecology, University of Cukurova School of Medicine, between January 2011 and July 2015 for routine mid-trimester fetal ultrasonography were retrospectively reviewed. The control (age: 18-34 years), advanced maternal age (35-39 years), and very advanced maternal age (>40 years) groups included 471, 399, and 87 women, respectively. Results: Gestational diabetes, gestational hypertension, and cesarean delivery rates were more common in the very advanced maternal age group, with compared with the advanced maternal age and the younger age group. There were no significant differences in regarding rates of spontaneous preterm delivery before 34 weeks of gestation, prolonged rupture of membranes, large for gestational age infants, and operative vaginal delivery rates between the groups. Also, there were no significant differences regarding in APGAR scores, the rate of low birth weight infants, and neonatal morbidity rates between the groups. However, admission to the neonatal intensive care unit requirement was more common in the two advanced maternal age groups compared with the control group. Conclusion: Advanced maternal age is a risk factor for gestational diabetes mellitus, gestational hypertension, preeclampsia, small for gestational age infants, spontaneous late preterm delivery, and cesarean section, with significant potential clinical implications.en_US
dc.identifier.doi10.1186/s12884-018-1984-x
dc.identifier.issn1471-2393
dc.identifier.pmid30134873en_US
dc.identifier.scopus2-s2.0-85052140786en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1186/s12884-018-1984-x
dc.identifier.urihttps://hdl.handle.net/11616/98441
dc.identifier.volume18en_US
dc.identifier.wosWOS:000442505700002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofBmc Pregnancy and Childbirthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMaternal ageen_US
dc.subjectNulliparityen_US
dc.subjectPreeclampsiaen_US
dc.subjectPregnancy outcomesen_US
dc.subjectSmall for gestational ageen_US
dc.titleThe effect of advanced maternal age on perinatal outcomes in nulliparous singleton pregnanciesen_US
dc.typeArticleen_US

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