1H magnetic resonance spectroscopy of the normal testis

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dc.authoridKahraman, Bayram/0000-0002-5447-1110
dc.authoridErdem, Gülnur/0000-0003-2200-8620
dc.authoridKarakas, Hakki/0000-0002-1328-8520
dc.authoridugras, meltem/0000-0001-9634-1229
dc.authorwosidKahraman, Bayram/HKM-4798-2023
dc.authorwosidErdem, Gülnur/GPS-7725-2022
dc.contributor.authorFirat, Ahmet Kemal
dc.contributor.authorUgras, Murat
dc.contributor.authorKarakas, Hakk M.
dc.contributor.authorErdem, Gulnur
dc.contributor.authorKurus, Meltem
dc.contributor.authorUgras, Meltem
dc.contributor.authorCelik, Tayfun
dc.date.accessioned2024-08-04T20:30:39Z
dc.date.available2024-08-04T20:30:39Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: The purpose of this study was to determine the pre- and postpubertal H-1 magnetic resonance spectroscopic characteristics of the normal testis to establish baseline values for further clinical studies. Materials and Methods: The subjects consisted of male volunteers, of whom 19 were prepubertal with ages between 7 and 13 years and 24 were postpubertal with ages between 19 and 39 years. Their testes were evaluated at 1.5 T with magnetic resonance spectroscopy; in addition, testis volumes were measured. Major metabolite peaks were identified and their ratios were calculated. Metabolite differences of testis between pre- and postpubertal age were analyzed. Results: Major constituents of spectra were 3.21 ppm choline and 0.9-1.3 ppm lipid peaks. At the echo time (TE) spectrum of 31 ms, choline/lipid ratios ranged from 0.35 to 8.30 (mean=1.87) in postpubertal males and from 0.06 to 5.45 (mean=0.88) in prepubertal males (P<.013). At the TE spectrum of 136 ms, choline/lipid ratios ranged from 0.66 to 15.42 (mean=4.09) in postpubertal males and from 0.05 to 4.91 (mean=0.9) in prepubertal males (P<.016). Conclusions: Choline/lipid ratio was higher in the postpubertal period. The existence of higher choline peak in that age group should be due to the initiation of spermatogenesis. The decrease in the lipid peak may represent the effect of testosterone on testicular tissue or may be due to histochemical changes initiated by puberty. The significant decrease in choline/lipid ratio noted after puberty could represent the presence of spermatogenesis. This hypothesis should be evaluated by further studies on postpubertal. subjects with impaired spermatogenesis. (C) 2008 Published by Elsevier Inc.en_US
dc.identifier.doi10.1016/j.mri.2007.06.008
dc.identifier.endpage220en_US
dc.identifier.issn0730-725X
dc.identifier.issue2en_US
dc.identifier.pmid17728090en_US
dc.identifier.scopus2-s2.0-38349094164en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage215en_US
dc.identifier.urihttps://doi.org/10.1016/j.mri.2007.06.008
dc.identifier.urihttps://hdl.handle.net/11616/94431
dc.identifier.volume26en_US
dc.identifier.wosWOS:000253225700008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofMagnetic Resonance Imagingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecttestisen_US
dc.subjectinfertilityen_US
dc.subjectcholineen_US
dc.subjectlipiden_US
dc.subjectmagnetic resonance spectroscopyen_US
dc.title1H magnetic resonance spectroscopy of the normal testisen_US
dc.typeArticleen_US

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