Malatya and Other Criteria for Liver Transplantation in Hepatocellular Carcinoma

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dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridince, volkan/0000-0002-0714-490X
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidince, volkan/M-7325-2017
dc.contributor.authorInce, Volkan
dc.contributor.authorAra, Cengiz
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-08-04T20:49:04Z
dc.date.available2024-08-04T20:49:04Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose Liver transplantation is a curative treatment option for hepatocellular carcinoma. In this review, we aimed to review liver transplantation criteria for hepatocellular carcinoma and patient survivals. Methods We reviewed literature in terms of liver transplant criteria for hepatocellular carcinoma. Patient eligibility criteria, post-transplant survivals, tumor recurrence and expansion of Milan criteria rates were analyzed. Results The Milan criteria, after being published in 1996, have become for deceased donor liver transplantation in hepatocellular carcinoma worldwide. Later, many transplant centers published their own liver transplant criteria. Most of the criteria consisted of morphological tumor characteristics based on tumor size and number. The newest published one is Malatya criteria. The 5-year overall survival according the all of the criteria is greater than 50%. There were just one paper which compare criteria according to survival and Malatya criteria were the best amongst extended criteria with 5-year OS 79.7% in that study. Conclusion It is clear that morphological criteria consisting only of tumor size and number are insufficient in patient selection for liver transplantation and should thus be combined with biological, inflammatory, radiological, pathological and genetic markers that predict the biological behavior of the tumor. Efforts to find the best criteria are still ongoing and 5-year overall survival should be greater than 60%.en_US
dc.identifier.doi10.1007/s12029-020-00484-y
dc.identifier.endpage1121en_US
dc.identifier.issn1941-6628
dc.identifier.issn1941-6636
dc.identifier.issue4en_US
dc.identifier.pmid32860615en_US
dc.identifier.scopus2-s2.0-85094982655en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1118en_US
dc.identifier.urihttps://doi.org/10.1007/s12029-020-00484-y
dc.identifier.urihttps://hdl.handle.net/11616/99612
dc.identifier.volume51en_US
dc.identifier.wosWOS:000563756600001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Gastrointestinal Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLive donoren_US
dc.subjectExtended criteriaen_US
dc.subjectLiver canceren_US
dc.subjectExpansion rateen_US
dc.titleMalatya and Other Criteria for Liver Transplantation in Hepatocellular Carcinomaen_US
dc.typeReview Articleen_US

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