What is the Importance of Demodex folliculorum and D. brevis in the etiology of blepharitis?

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dc.authorscopusid14038550900
dc.authorscopusid55584788000
dc.authorscopusid22978273500
dc.authorscopusid6701346723
dc.authorscopusid22979099500
dc.authorscopusid23029212900
dc.contributor.authorYula E.
dc.contributor.authorAycan Kaya Ö.M.
dc.contributor.authorAtambay M.
dc.contributor.authorDo?anay S.
dc.contributor.authorDaldal N.
dc.contributor.authorAyhan Tuzcu E.
dc.date.accessioned2024-08-04T20:00:54Z
dc.date.available2024-08-04T20:00:54Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: It was reported that, Demodex folliculorum (DF) and D. brevis (DB) may cause an infestation in healthy subjects and, may be important for some eye problems such as blepharitis, or these parasites can bring the present disease into a more serious condition. In this study, we aimed to determine which demodex species' density increase in patients with blepharitis and whether the demodex density on face differs from healthy subjects. Material and Methods: In the study, the presence of demodex species was analyzed on eyelashes and faces of 96 patients with blepharitis and 197 healthy subjects. Samples taken through standard superficial skin biopsy technique and eyelash epilation were analyzed with the light microscope. Results: The mean age of the patients with blepharitis was 46.90±16.92 (15-89) years, whereas the mean age of control group was 39.54±17.61 (12-84) years. Among eyelash samples of the patients, 78 (81.25%) samples were found DF positive, whereas 25 (26.04%) of them were found DB positive; on the contrary 30 (15.22%) and 7 (3.55%) of the control group was DF and DB positive, respectively. Among the eyelash samples of the patients, the demodex incidence was statistically significantly higher compared to the control group (p<0.001). There was no significant difference in terms of demodex positivities on face. All patients who were demodex positive on the facial area were also found demodex positive for eyelash samples whereas 8 (24.2%) of eyelash samples were Demodex spp positive in the control group (p<0.001). Conclusion: The results of our study underline that the presence of Demodex spp on facial area may be one the important factors in the pathogenesis of blepharitis. In conclusion, we suggest that taking the demodicosis presence into consideration as a worsening factor may help in the management of blepharitis. © 2013 by Türkiye Klinikleri.en_US
dc.identifier.doi10.5336/medsci.2012-29698
dc.identifier.endpage424en_US
dc.identifier.issn1300-0292
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84874629954en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage420en_US
dc.identifier.urihttps://doi.org/10.5336/medsci.2012-29698
dc.identifier.urihttps://hdl.handle.net/11616/91096
dc.identifier.volume33en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTurkiye Kliniklerien_US
dc.relation.ispartofTurkiye Klinikleri Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBlepharitisen_US
dc.subjectEctoparasitic infestationsen_US
dc.titleWhat is the Importance of Demodex folliculorum and D. brevis in the etiology of blepharitis?en_US
dc.title.alternativeBlefarit etiyolojisinde demodex folliculorum ve D. brevis'in önemi nedir?en_US
dc.typeArticleen_US

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