Corneal Endothelial Changes in Behcet's Patients with Inactive Ocular Involvement

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dc.authoridGündüz, Abuzer/0000-0003-1752-6810
dc.authoridcankaya, cem/0000-0002-7716-0438
dc.authoridTuncer Firat, Ilknur/0000-0003-1491-8659
dc.authorwosidCankaya, Cem/HTR-3803-2023
dc.authorwosidGündüz, Abuzer/HLH-2417-2023
dc.authorwosidcankaya, cem/ABH-6458-2020
dc.contributor.authorCankaya, Cem
dc.contributor.authorCumurcu, Tongabay
dc.contributor.authorGunduz, Abuzer
dc.contributor.authorFirat, Ilknur
dc.date.accessioned2024-08-04T20:44:34Z
dc.date.available2024-08-04T20:44:34Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: The purpose of this article is to evaluate alterations in the corneal endothelial layer in Behcet's disease (BD) with inactive ocular involvement using specular microscopy.Materials and Methods: Thirty-three eyes of 33 BD patients who had at least one anterior segment involvement and no active inflammation in the last 3months were included in the study (group 1). Twenty-seven of the 33 BD patients had an anterior uveitis attack and six of them had a panuveitis (both anterior and posterior involvement) attack. Thirty-three eyes of 33 age- and sex-matched healthy subjects were enrolled in the control group (group 2). Corneal endothelial cell density (CD), coefficient of variation (CV), hexagonal cell ratio (HEX), and central corneal thickness (CCT) were measured using specular microscopy (Konan Medical, Nishinomiya, Japan), and the results were compared between groups.Results: The mean CD was 2739164.18 cells/mm(2) in group 1 and 2922 +/- 107.60 cells/mm(2) in group 2 (p=0.001). The mean CV was 32.9 +/- 4.76 in group 1 and 28.5 +/- 3.06 in group 2 (p=0.001). The mean HEX was 44.7 +/- 6.51 in group 1 and 49.7 +/- 6.10 in group 2 (p=0.019). The mean CCT was 545.75 +/- 40.89 in group 1 and 545.66 +/- 30.09 in group 2 (p>0.05).Conclusions: Ocular attacks in our BD patients may have caused permanent changes in the corneal endothelial layer. However, these changes did not lead to corneal decompensation, but further studies are necessary to confirm these results.en_US
dc.identifier.doi10.1080/02713683.2018.1472285
dc.identifier.endpage971en_US
dc.identifier.issn0271-3683
dc.identifier.issn1460-2202
dc.identifier.issue8en_US
dc.identifier.pmid29715058en_US
dc.identifier.scopus2-s2.0-85047928881en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage965en_US
dc.identifier.urihttps://doi.org/10.1080/02713683.2018.1472285
dc.identifier.urihttps://hdl.handle.net/11616/98313
dc.identifier.volume43en_US
dc.identifier.wosWOS:000439721700002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofCurrent Eye Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectInactive Behcet's diseaseen_US
dc.subjectcorneaen_US
dc.subjectcorneal endothelial morphologyen_US
dc.subjectspecular microscopyen_US
dc.titleCorneal Endothelial Changes in Behcet's Patients with Inactive Ocular Involvementen_US
dc.typeArticleen_US

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