c-Kit proto-oncogene expression in endometrial hyperplasia and endometrial cancer

dc.authoridGül, Mehmet/0000-0002-1374-0783
dc.authoridCelik, ebru/0000-0002-0774-4294
dc.authoridAYDIN, Nasuhi/0000-0003-3145-2432
dc.authoridTURKCUOGLU, ILGIN/0000-0002-8342-1956
dc.authorwosidAydin, Nasuhi E/B-6536-2012
dc.authorwosidGül, Mehmet/ABI-6336-2020
dc.authorwosidCelik, ebru/X-4343-2019
dc.authorwosidSimsek, Yavuz/AAH-9894-2021
dc.authorwosidAYDIN, Nasuhi/O-9043-2016
dc.contributor.authorYilmaz, Ercan
dc.contributor.authorCelik, Onder
dc.contributor.authorSimsek, Yavuz
dc.contributor.authorTurkcuoglu, Ilgin
dc.contributor.authorCelik, Ebru
dc.contributor.authorGul, Mehmet
dc.contributor.authorHascalik, Seyma
dc.date.accessioned2024-08-04T20:36:03Z
dc.date.available2024-08-04T20:36:03Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTo evaluate the expression of c-kit (CD117) in endometrial hyperplasia and endometrial cancer. Expression of c-kit in 10 normal endometrium, 18 simple endometrial hyperplasia, 16 complex endometrial hyperplasia (10 cases with atypia and 6 cases without atypia), and 6 endometrial cancer were investigated by immunohistochemistry. c-Kit expression decreased as the lesion progressed to endometrial cancer. Immunostaining was mostly focal and weak in the normal endometrium and was mostly diffuse and strong in the simple and complex endometrial hyperplasia. Simple and complex hyperplastic endometrial tissues express diffuse cytoplasmic staining for c-kit and the expression decreases with the progression of the lesion.en_US
dc.identifier.doi10.1007/s00404-012-2276-8
dc.identifier.endpage200en_US
dc.identifier.issn0932-0067
dc.identifier.issue1en_US
dc.identifier.pmid22392489en_US
dc.identifier.scopus2-s2.0-84864444468en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage197en_US
dc.identifier.urihttps://doi.org/10.1007/s00404-012-2276-8
dc.identifier.urihttps://hdl.handle.net/11616/95758
dc.identifier.volume286en_US
dc.identifier.wosWOS:000305211300034en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofArchives of Gynecology and Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEndometrial hyperplasiaen_US
dc.subjectEndometriumen_US
dc.subjectc-Kiten_US
dc.subjectCD117en_US
dc.subjectEndometrial canceren_US
dc.titlec-Kit proto-oncogene expression in endometrial hyperplasia and endometrial canceren_US
dc.typeArticleen_US

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