Elevated serum CA-125 levels in patients with nephrotic syndrome-induced ascites

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dc.authoridSevinç, Alper/0000-0002-0499-8918
dc.authoridTÜRK, Haci Mehmet/0000-0003-2206-8148;
dc.authorwosidSevinç, Alper/KPA-4519-2024
dc.authorwosidSari, Ramazan/C-2868-2016
dc.authorwosidTÜRK, Haci Mehmet/B-5013-2015
dc.authorwosidSevinc, Alper/KFQ-6440-2024
dc.contributor.authorSevinc, A
dc.contributor.authorBuyukberber, S
dc.contributor.authorSari, R
dc.contributor.authorTurk, HM
dc.contributor.authorAtes, M
dc.date.accessioned2024-08-04T20:12:10Z
dc.date.available2024-08-04T20:12:10Z
dc.date.issued2000
dc.departmentİnönü Üniversitesien_US
dc.description.abstractCA-125 is a sensitive, but not a specific, tumour marker especially used in the diagnosis and follow-up of ovarian cancer. Because of the elevated levels of CA-125 encountered during the etiological investigation of nephrotic syndrome (NS) a clinical study was designed to investigate the probable relationship between elevated CA-125 levels in patients with NS, with and without ascites. Twenty-four patients with NS due to non-tumoural pathologies, aged 24 to 56 (15 females and 9 males), were investigated We detected elevated levels of serum CA-125 (275.92 +/- 154.71 U/mL) in 14 (70%) NS patients with ascites (p<0.05). In the other 10 NS patients without ascites (Group 2) and in the control group, consisting of 52 age and sex-marched healthy volunteers, the serum CA-125 levels were found to be 13.60 +/- 5.12 U/mL and 8.50 +/- 5.02 U/mL, respectively (p>0.05). There was no statistically significant difference between the control group and the patients without serosal fluids (p>0.05). We concluded that serum CA-125 levels were elevated in NS patients with ultrasonographically detected ascites in the absence of an ovarian tumour or other diseases known to increase the levels of CA-125.en_US
dc.identifier.endpage1203en_US
dc.identifier.issn0250-7005
dc.identifier.issue2Ben_US
dc.identifier.pmid10810422en_US
dc.identifier.scopus2-s2.0-0034107775en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1201en_US
dc.identifier.urihttps://hdl.handle.net/11616/93258
dc.identifier.volume20en_US
dc.identifier.wosWOS:000086764800025en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInt Inst Anticancer Researchen_US
dc.relation.ispartofAnticancer Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCA-125en_US
dc.subjectnephrotic syndromeen_US
dc.subjectascitesen_US
dc.titleElevated serum CA-125 levels in patients with nephrotic syndrome-induced ascitesen_US
dc.typeArticleen_US

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