Evaluation of peripapillary retinal nerve fiber layer, macula and ganglion cell thickness in amblyopia using spectral optical coherence tomography

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dc.authoridBozgul, Pembegul/0000-0002-9427-3610
dc.authoridGündüz, Abuzer/0000-0003-1752-6810
dc.authorwosidBozgul, Pembegul/AAQ-4951-2020
dc.authorwosidGündüz, Abuzer/HLH-2417-2023
dc.contributor.authorFirat, Penpe Gul
dc.contributor.authorOzsoy, Ercan
dc.contributor.authorDemirel, Soner
dc.contributor.authorCumurcu, Tongabay
dc.contributor.authorGunduz, Abuzer
dc.date.accessioned2024-08-04T20:38:01Z
dc.date.available2024-08-04T20:38:01Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAIM: To investigate peripapillary retinal nerve fiber layer (RNFL), macula and ganglion cell layer thicknesses (GCC) in amblyopic eyes with spectral domain optical coherence tomography (SD-OCT). METHODS: Thirty six patients with a history of unilateral amblyopia and thirty two children who had emmetropia without amblyopia were included in this study. In this institutional study, 36 eyes of 36 patients with amblyopia (AE), 36 fellow eyes without amblyopia (FE), and 32 eyes of 32 normal subjects (NE) were included. RNFL, GCC and macular thickness measurements were performed with RS-3000 OCT Retina Scan (Nidek Inc CA. USA). RESULTS: The mean global thicknesses of the RNFL were 113.22 +/- 121.47, 111.57 +/- 18.25, 109.96 +/- 11.31 mu m in the AE, FE, and NE, respectively. There was no statistically significant difference for mean global RNFL thickness among the eyes (P=0.13). The mean thicknesses of the macula were 258.25 +/- 18.31, 258.75 +/- 19.54, 248.62 +/- 10.57 mu m in the AE, FE and NE, respectively. There was no statistically significant difference for thickness of macula among the eyes (P=0.06). The GCC was investigated into two parts: superior and inferior. The mean thicknesses of superior GCC were 102.57 +/- 113.32, 103.32 +/- 10.64, 100.52 +/- 15.88 mu m in the AE, FE, and NE, respectively. The mean thicknesses of inferior GCC were 103.82 +/- 112.60, 107.82 +/- 12.33, 105.86 +/- 10.79 mu m in the AE, FE and NE, respectively. There was no statistically significant difference for thickness of superior and inferior GCC between the eyes (P=0.63, P=0.46). CONCLUSION: The macular thicknesses of AE and FE were greater than the NE, although it was not statistically significant. Amblyopia does not seem to have a profound effect on the RNFL, macula and GCC.en_US
dc.identifier.doi10.3980/j.issn.2222-3959.2013.01.19
dc.identifier.endpage94en_US
dc.identifier.issn2222-3959
dc.identifier.issue1en_US
dc.identifier.pmid23550060en_US
dc.identifier.scopus2-s2.0-84891485501en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage90en_US
dc.identifier.urihttps://doi.org/10.3980/j.issn.2222-3959.2013.01.19
dc.identifier.urihttps://hdl.handle.net/11616/96311
dc.identifier.volume6en_US
dc.identifier.wosWOS:000315180600019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherIjo Pressen_US
dc.relation.ispartofInternational Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectamblyopiaen_US
dc.subjectretinal nerve fiber layeren_US
dc.subjectmaculaen_US
dc.subjectganglion cell complexen_US
dc.titleEvaluation of peripapillary retinal nerve fiber layer, macula and ganglion cell thickness in amblyopia using spectral optical coherence tomographyen_US
dc.typeArticleen_US

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