Oxidative stress and altered levels of antioxidants in adolescents with Down syndrome during pre-exercise and post-exercise

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dc.authoridErisir, Mine/0000-0001-6209-4792
dc.authorwosidÖzbey, Ülkü/AAF-7617-2019
dc.contributor.authorOzbey, Ulku
dc.contributor.authorArslan, Cengiz
dc.contributor.authorSavucu, Yuksel
dc.contributor.authorErisir, Mine
dc.contributor.authorSeyran, Ayse
dc.date.accessioned2024-08-04T21:00:08Z
dc.date.available2024-08-04T21:00:08Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to determine the influence of exercise on activity of erythrocyte superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) and plasma malondialdehyde (MDA), beta-carotene, retinol levels in adolescents with Down syndrome (DS). Twenty adolescents with DS (14.86 +/- 7.07 years) performed a 12-week training program. Body composition was measured by bioelectric impedance method. SOD, GPx, CAT, MDA, retinol, beta-carotene levels was determined spectrophotometrically. When compared to baseline, MDA level was increased (P<0.05). SOD, GPx activities and beta-carotene level were decreased (P<0.05). There was no difference during pre-post exercise in terms of CAT activity and retinol level (P>0.05). The mean value of percentage of fat mass was reduced. Regular exercise decreased SOD, GPx activities and beta-carotene level and did not affect CAT activity and retinol level in individuals with DS. Exercise increases oxidative stress depending on level of training.en_US
dc.identifier.doi10.5897/AJMR11.1621
dc.identifier.endpage5630en_US
dc.identifier.issn1996-0808
dc.identifier.issue27en_US
dc.identifier.startpage5625en_US
dc.identifier.urihttps://doi.org/10.5897/AJMR11.1621
dc.identifier.urihttps://hdl.handle.net/11616/103823
dc.identifier.volume6en_US
dc.identifier.wosWOS:000307508800014en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAcademic Journalsen_US
dc.relation.ispartofAfrican Journal of Microbiology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDown syndromeen_US
dc.subjectexerciseen_US
dc.subjectbody compositionen_US
dc.subjectantioxidant enzymeen_US
dc.subjectobesityen_US
dc.subjectfat mass percentageen_US
dc.titleOxidative stress and altered levels of antioxidants in adolescents with Down syndrome during pre-exercise and post-exerciseen_US
dc.typeArticleen_US

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