Determination of Salbutamol Sulfate in pharmaceutical formulation with differential pulse voltammetry using poly(Benzofuran-2-Boronic a cid) modified platinum electrode

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dc.contributor.authorGüngör, Öznur
dc.date.accessioned2024-08-04T19:42:54Z
dc.date.available2024-08-04T19:42:54Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, determination of salbutamol sulfate (SBS) was carried out using poly(benzofuran-2-boronic acid)/platinum electrode (BF2BA/PtE). Polymerization of BF2BA was conducted in acetonitrile (AcN) containing 0.1 M sodium perchlorate (NaClO4) on bare PtE by cyclic voltammetry (CV) method. The electrochemical properties of the prepared polymer electrode were investigated by CV and electrochemical impedance spectroscopy (EIS) techniques in ferricyanide/KNO3 solution. Then, prepared poly(BF2BA/PtE) was used for detection of the SBS. Monomer type, concentration, the number of cycles and scan rate were worked using differential pulse voltammetry (DPV) in citrate-phosphate buffer containing 1.15 mM SBS. The effects of parameters such as electrolyte type, pH effect on SBS DPV responses were studied. The SBS responses of the modified electrodes were also investigated by square wave voltammetry (SWV). The oxidative current peak stem from SBS concentration showed at 0.65V potential and a linear calibration curve was obtained in the range from 50 to 2000 ?M SBS concentration. Limit of dedection (LOD), and limit of quantitation (LOQ), was calculated as 49.14 ?M and 163.80 ?M, respectively. The recovery efficiency for synthetic urine samples was obtained from 91.47 to 110.43% by using BF2BA/PtE.en_US
dc.identifier.endpage628en_US
dc.identifier.issn2587-2680
dc.identifier.issn2587-246X
dc.identifier.issue3en_US
dc.identifier.startpage616en_US
dc.identifier.trdizinid1109264en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1109264
dc.identifier.urihttps://hdl.handle.net/11616/88783
dc.identifier.volume42en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofCumhuriyet Science Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleDetermination of Salbutamol Sulfate in pharmaceutical formulation with differential pulse voltammetry using poly(Benzofuran-2-Boronic a cid) modified platinum electrodeen_US
dc.typeArticleen_US

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