Community-acquired acute bacterial meningitis in the elderly in Turkey

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dc.authoridKILIÇ ERCİYAS, Seda/0000-0003-4417-4005
dc.authoridErdem, Hakan/0000-0002-6265-5227
dc.authoridöngürü, pınar/0000-0002-1638-3160
dc.authoridErsoy, Yasemin/0000-0001-5730-6682
dc.authorwosidKILIÇ ERCİYAS, Seda/P-9346-2015
dc.authorwosidErdem, Hakan/O-2462-2013
dc.authorwosidARTUK, Cumhur/B-1552-2016
dc.authorwosidÇağatay, Atahan/AAE-2343-2020
dc.authorwosidöngürü, pınar/IYS-4918-2023
dc.authorwosidAlp Çavuş, Sema/A-3643-2019
dc.authorwosidKurtaran, Behice/E-9577-2018
dc.contributor.authorErdem, H.
dc.contributor.authorKilic, S.
dc.contributor.authorCoskun, O.
dc.contributor.authorErsoy, Y.
dc.contributor.authorCagatay, A.
dc.contributor.authorOnguru, P.
dc.contributor.authorAlp, S.
dc.date.accessioned2024-08-04T20:32:28Z
dc.date.available2024-08-04T20:32:28Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractP>This investigation aimed both to delineate the current status of community-acquired acute bacterial meningitis and to produce data on the interrelationships between clinical, laboratory and therapeutic parameters in the elderly. This retrospective cohort study was conducted in 28 Turkish institutions in 159 culture-positive patients over the age of 50 years. Streptococcus pneumoniae was the most common pathogen (69.2%), followed by Listeria monocytogenes (8.8%). For this reason, antilisterial antibiotics such as ampicillin or benzylpenicillin should be added to the therapeutic regimen. Pathogen-specific mortality did not vary between S. pneumoniae and L. monocytogenes. The overall mortality was 2.5% at the third day, 12.6% at the seventh day, 20.1% at the 14th day and 21.4% at the 21st day. The risk factors for fatality were increasing age, the presence of stupor, sepsis and inappropriate antibiotic administration. Cerebrospinal fluid (CSF) leukocyte counts and CSF/blood glucose ratios were lower in patients who died. Fever did not differ between survivors and fatal cases. The mean duration of antibiotic therapy in survivors was 16.3 +/- 6.4 days. One-fifth of the patients had complications, and in 5.7% of the patients sequelae persisted at follow-up.en_US
dc.identifier.doi10.1111/j.1469-0691.2009.03039.x
dc.identifier.endpage1229en_US
dc.identifier.issn1198-743X
dc.identifier.issn1469-0691
dc.identifier.issue8en_US
dc.identifier.pmid19732089en_US
dc.identifier.scopus2-s2.0-77955129768en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1223en_US
dc.identifier.urihttps://doi.org/10.1111/j.1469-0691.2009.03039.x
dc.identifier.urihttps://hdl.handle.net/11616/95094
dc.identifier.volume16en_US
dc.identifier.wosWOS:000280359900031en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofClinical Microbiology and Infectionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcuteen_US
dc.subjectcommunity-acquireden_US
dc.subjectelderlyen_US
dc.subjectmeningitisen_US
dc.subjectTurkeyen_US
dc.titleCommunity-acquired acute bacterial meningitis in the elderly in Turkeyen_US
dc.typeArticleen_US

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