Evaluation of lipid levels and LDL-C/HDL-C ratio as possible risk markers of intracerebral hemorrhage

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dc.authoridAdiguzel, Ahmet/0000-0001-5197-7063
dc.authoridCiplak, Sibel/0000-0002-2304-8125
dc.authorwosidAdiguzel, Ahmet/GPG-3954-2022
dc.contributor.authorAdiguzel, Ahmet
dc.contributor.authorCiplak, Sibel
dc.contributor.authorOzturk, Unal
dc.date.accessioned2024-08-04T20:10:34Z
dc.date.available2024-08-04T20:10:34Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: The aim of this study is to analyze the utility of lipid parameters individually and the low-density lipoprotein cholesterol/high-density lipoprotein cholesterol (LDL-C/HDL-C) ratio as a possible risk marker for intracerebral hemorrhages (ICH). Materials and Methods: This was a multicenter, retrospective case-control study that included 226 patients with ICH and 226 controls. Lipid parameters were evaluated after 12 h of fasting in patients whose ICH was confirmed by brain computed tomography, and no underlying vascular, traumatic, or metabolic cause could be found. Results: The mean LDL-C levels and mean total cholesterol (TC) levels did not differ in in the patient and control groups. The mean HDL-C levels in the patient groups were significantly lower whereas triglyceride (TG) levels were significantly higher. In the patient and control groups, LDL-C/HDL-C ratio was 2.65 +/- 1.10 and 2.94 +/- 1.13 (p=0.006), TG/HDL-C ratio was 3.60 +/- 2.72 and 4.47 +/- 3.25 (p=0.002), and TC/HDL-C ratio was 4.37 +/- 1.49 and 4.83 +/- 1.56 (p=0.002), respectively. Conclusion: Increased TG and decreased HDL-C levels were found to be associated with ICHs. However LDL-C/HDL-C, TC/HDL-C, and TG/HDL-C ratios were low in the patient group. Therefore, we can conclude that these lipid ratios give clearer and more significant results in determining the risk of hemorrhage.en_US
dc.identifier.doi10.17826/cumj.1030321
dc.identifier.endpage127en_US
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.issue1en_US
dc.identifier.startpage120en_US
dc.identifier.trdizinid519925en_US
dc.identifier.urihttps://doi.org/10.17826/cumj.1030321
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/519925
dc.identifier.urihttps://hdl.handle.net/11616/92876
dc.identifier.volume47en_US
dc.identifier.wosWOS:000767959700016en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherCukurova Univ, Fac Medicineen_US
dc.relation.ispartofCukurova Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLDL-C/HDL-C ratioen_US
dc.subjecttriglyceride/HDL-C ratioen_US
dc.subjecthemorrhagic strokeen_US
dc.subjectcholesterolen_US
dc.subjectcerebrovascular diseaseen_US
dc.titleEvaluation of lipid levels and LDL-C/HDL-C ratio as possible risk markers of intracerebral hemorrhageen_US
dc.typeArticleen_US

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