The relation of neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and mean platelet volume with idiopathic acute anterior uveitis

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dc.contributor.authorDemir, Ulku
dc.date.accessioned2024-08-04T20:55:02Z
dc.date.available2024-08-04T20:55:02Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: In this study leukocyte, lymphocyte, neutrophil, platelet count, mean platelet volume (MPV), neutrophil/lymphocyte (NLR) ratio and platelet/lymphocyte ratio (PLR) were retrospectively evaluated in patients with idiopathic acute anterior uveitis. Materials and methods: Medical records were retrospectively reviewed from March 2016 to February 2020. Fifty patients (25 men and 25 women) and as the control group, 50 healthy volunteers (25 males and 25 females) were included in this study. Blood samples of the patients were taken before starting treatment. A complete ophthalmological examination, including corrected visual acuity, tonometry, slit lamp and fundus examination, was performed in all patients. Gender, age, leukocyte, neutrophil, lymphocyte, platelet, MPV, PLR, and NLR values of the patients were recorded. Results: In this study, a statistically significant difference was found in leukocyte (p < .001), neutrophil (p < .001), platelet (p < .001), NLR (p < .001) and PLR (p < .001) values. No significant difference was found between the two groups in terms of lymphocyte count (p = .063) and in the MPV value (p = .051). Leukocyte, neutrophil, platelet count, NLR, and PLR values were higher in the uveitis group compared to the control group. In the receiver operating characteristic (ROC) curve analysis, the area under the curve (AUC) for NLR was 0.805, with a sensitivity of 56.0% and a specificity of 98.0%. The AUC for PLR was 0.657, with a sensitivity of 52.0% and a specificity of 98.0%. Conclusion: In this retrospective study, leukocyte, neutrophil, platelet count, PLR, and NLR levels were significantly higher in patients with idiopathic acute anterior uveitis compared to the control group. These blood parameters are useful as diagnostic markers and can be used in early diagnosis.en_US
dc.identifier.doi10.1177/1721727X231216196
dc.identifier.issn1721-727X
dc.identifier.issn2058-7392
dc.identifier.scopus2-s2.0-85183901089en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.urihttps://doi.org/10.1177/1721727X231216196
dc.identifier.urihttps://hdl.handle.net/11616/101794
dc.identifier.volume22en_US
dc.identifier.wosWOS:001153853000001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofEuropean Journal of Inflammationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectplatelet/lymphocyte ratioen_US
dc.subjectneutrophil/lymphocyte ratioen_US
dc.subjectinflammationen_US
dc.subjectuveitisen_US
dc.subjectblood parametersen_US
dc.titleThe relation of neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and mean platelet volume with idiopathic acute anterior uveitisen_US
dc.typeArticleen_US

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