The use of magnesium to prevent laryngospasm after tonsillectomy and adenoidectomy: a preliminary study

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dc.authoridDurmus, Mahmut/0000-0001-9594-9064
dc.authoridGulhas, Nurcin/0000-0002-2539-9017
dc.authoridErsoy, Mehmet/0000-0002-0724-2825
dc.authorwosidDurmus, Mahmut/ABH-3006-2020
dc.authorwosidGulhas, Nurcin/A-7281-2018
dc.authorwosidErsoy, Mehmet/ACN-2779-2022
dc.contributor.authorGulhas, N
dc.contributor.authorDurmus, M
dc.contributor.authorDemirbilek, S
dc.contributor.authorTogal, T
dc.contributor.authorOzturk, E
dc.contributor.authorErsoy, MO
dc.date.accessioned2024-08-04T20:13:13Z
dc.date.available2024-08-04T20:13:13Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground : Laryngospasm is the most common cause of upper airway obstruction after tracheal extubation. Magnesium has a central nervous system depressant property, which contributes to the depth of anaesthesia. It also has calcium antagonist properties, which provide muscle relaxation. In this study, we aimed to determine the effect of magnesium on preventing laryngospasm. Methods : After approval of the Ethics Committee and informed parental consent, 40 patients, ASA I-II, aged 3-12 years, who were scheduled for tonsillectomy or/and adenoidectomy, were randomly divided into two groups. Anaesthesia was induced with sevoflurane, lidocaine 1 mg.kg(-1) , alfentanil 10 mug.kg(-1) , vecuronium 0.1 mg.kg(-1) and maintained with sevoflurane 2% and 60% nitrous oxide in oxygen. After intubation, patients in group I received 15 mg.kg(-1) magnesium in 30 ml 0.9% NaCl over 20 min. Patients in group II received 0.9% NaCl alone in the same volume. After reversal of neuromuscular blockade, all patients were extubated at a very deep plane of anaesthesia. The incidence of laryngospasm was determined until the time of discharge from the postanaesthesia care unit. Results : Although laryngospasm was not observed in group I, it was observed in five patients in group II (25%). The incidence of laryngospasm in group II was significantly higher than group I. The plasma magnesium concentrations were significantly higher in group I than group II. Conclusions : We found a significant decrease in the incidence of laryngospasm in paediatric patients receiving magnesium. It is suggested that the use of intravenous magnesium intraoperatively may prevent laryngospasm.en_US
dc.identifier.doi10.1046/j.1460-9592.2003.00927.x
dc.identifier.endpage47en_US
dc.identifier.issn1155-5645
dc.identifier.issue1en_US
dc.identifier.pmid12535038en_US
dc.identifier.scopus2-s2.0-0037238545en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage43en_US
dc.identifier.urihttps://doi.org/10.1046/j.1460-9592.2003.00927.x
dc.identifier.urihttps://hdl.handle.net/11616/93476
dc.identifier.volume13en_US
dc.identifier.wosWOS:000180433300008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBlackwell Publishing Ltden_US
dc.relation.ispartofPaediatric Anaesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmagnesiumen_US
dc.subjectlaryngospasmen_US
dc.subjectadenotonsillectomyen_US
dc.titleThe use of magnesium to prevent laryngospasm after tonsillectomy and adenoidectomy: a preliminary studyen_US
dc.typeArticleen_US

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