Evaluation of Antimicrobial Activities of Topical Anesthetics

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dc.authoridcankaya, cem/0000-0002-7716-0438
dc.authoridOTLU, BARIS/0000-0002-6220-0521
dc.authoridGünal, Selami/0000-0002-4752-5176;
dc.authorwosidcankaya, cem/ABH-6458-2020
dc.authorwosidorman, gözde/JEP-3740-2023
dc.authorwosidOTLU, BARIS/ABI-5532-2020
dc.authorwosidCankaya, Cem/HTR-3803-2023
dc.authorwosidGünal, Selami/AAA-7246-2021
dc.authorwosidORMAN, GÖZDE/HNQ-4152-2023
dc.contributor.authorOrman, Gozde
dc.contributor.authorCankaya, Cem
dc.contributor.authorDoganay, Selim
dc.contributor.authorGunal, Selami
dc.contributor.authorOtlu, Baris
dc.date.accessioned2024-08-04T20:35:32Z
dc.date.available2024-08-04T20:35:32Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To investigate the antimicrobial activities of the drugs used as topical anesthetics. Material and Methods: Test drugs (oxybuprocaine 0.4%, proparacaine hydrochloride 0.5%, lidocaine 10%) were tested for Staphylococcus aureus (S. aureus) ATCC 29213, Streptococcus pneumoniae (S. pneumoniae)ATCC 27336, Pseudomonas aeruginosa (P. aeruginosa) ATCC 27853, standard strains of Escherichia coli (E. coli) ATCC 25922 and Candida albicans (C. albicans) using modified microplate alamar blue method (MABA) in different concentrations according to Clinical and Laboratory Standards Institute (CLSI) criteria. Results: S. Pneumoniae proliferated in none of the dilutions of three topical anesthetics. S. aureus proliferated in all dilutions of oxybuprocaine and lidocaine and in no dilutions of proparacaine hydrochloride. P. Aeruginosa proliferated in 0.2% dilution of oxybuprocaine and 2.5% and 5% dilutions of lidocaine and in all dilutions of proparacaine hydrochloride. C. albicans proliferated in 0.05% and 0.025 % dilutions of oxybuprocaine, 1.25% and 0.625% dilutions of lidocaine, 0.125%, 0.0625% and 0.0312% dilutions of proparacaine hydrochloride. E. Coll proliferated in all dilutions of oxybuprocaine, 0.625% dilutions of lidocaine and 0.125%, 0.0625% and 0.0312% dilutions of proparacaine hydrochloride. Conclusio: Topical anesthetics that are used before sample collection in superficial ocular infections can cause false results in cultures by inhibating proliferations of microorganisms. Thus, it is important to know the effects of topical anesthetics and dilutions on bacterial proliferation.en_US
dc.identifier.doi10.5336/medsci.2009-15695
dc.identifier.endpage389en_US
dc.identifier.issn1300-0292
dc.identifier.issn2146-9040
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-80051714898en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage386en_US
dc.identifier.urihttps://doi.org/10.5336/medsci.2009-15695
dc.identifier.urihttps://hdl.handle.net/11616/95407
dc.identifier.volume31en_US
dc.identifier.wosWOS:000291330700016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherOrtadogu Ad Pres & Publ Coen_US
dc.relation.ispartofTurkiye Klinikleri Tip Bilimleri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnti-infective agents, localen_US
dc.subjectanesthetics, localen_US
dc.subjecteye infectionsen_US
dc.titleEvaluation of Antimicrobial Activities of Topical Anestheticsen_US
dc.typeArticleen_US

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