Remifentanil without muscle relaxants for intubation in microlaryngoscopy: a double blind randomised clinical trial

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dc.authoridbegeç, zekine/0000-0002-9506-1871
dc.authoridDurmus, Mahmut/0000-0001-9594-9064
dc.authoridYologlu, Saim/0000-0002-9619-3462
dc.authoridGulhas, Nurcin/0000-0002-2539-9017
dc.authoridErdogan Kayhan, Gulay/0000-0002-2635-9295
dc.authoridYücel, Aytaç/0000-0003-0270-8339
dc.authoridErsoy, Mehmet/0000-0002-0724-2825
dc.authorwosidbegeç, zekine/ABI-5491-2020
dc.authorwosidDurmuş, Mahmut/AAG-3377-2019
dc.authorwosidDurmus, Mahmut/ABH-3006-2020
dc.authorwosidYologlu, Saim/ABI-8014-2020
dc.authorwosidGulhas, Nurcin/A-7281-2018
dc.authorwosidErdogan Kayhan, Gulay/JVZ-0037-2024
dc.authorwosidYücel, Aytaç/ABI-6137-2020
dc.contributor.authorGulhas, N.
dc.contributor.authorTopal, S.
dc.contributor.authorKayhan, G. Erdogan
dc.contributor.authorYucel, A.
dc.contributor.authorBegec, Z.
dc.contributor.authorYologlu, S.
dc.contributor.authorDurmus, M.
dc.date.accessioned2024-08-04T20:37:51Z
dc.date.available2024-08-04T20:37:51Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVES: We aimed to compare the effect of remifentanil without muscle relaxant with succinylcholine for intubation in microlaryngoscopy. PATIENTS AND METHODS: Eighty patients were randomly divided into two groups: Group R (n=40) and S (n=40) received remifentanil 4 mu g/kg intravenously or 1 mu g/kg respectively. Anesthesia was induced with 2 mg/kg propofol in both groups. Intubation was performed after bolus administration of 10 ml saline as a placebo or 1 mg/kg of succinylcholine in Group R and S respectively. Remifentanil infusion was initiated at 0.025 mu g/kg in each groups. RESULTS: Intubation conditions were similar in both groups. The mean arterial pressure (MAP) values at post-induction period were significantly lower in the Group S than in the Group R (p = 0.001). The requirement for ephedrine in Group R was found to be significantly lower than Group S (p = 0.023). Recovery times were significantly shorter (p = 0.001) and recovery scores were significantly higher (p = 0.021) in Group R. Time to patient could respond to commands was significantly longer in the Group S (p = 0.001). The surgeon's satisfaction score was significantly higher in Group R (p = 0.001). CONCLUSIONS: It was concluded that remifentanil without muscle relaxants provides similar intubating conditions as that provided by succinylcholine, and remifentanil is superior to succinylcholine with regard to haemodynamic stability and recovery duration.en_US
dc.identifier.endpage1973en_US
dc.identifier.issn1128-3602
dc.identifier.issue14en_US
dc.identifier.pmid23877864en_US
dc.identifier.scopus2-s2.0-84884174037en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1967en_US
dc.identifier.urihttps://hdl.handle.net/11616/96203
dc.identifier.volume17en_US
dc.identifier.wosWOS:000325203900020en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMicrolaryngoscopyen_US
dc.subjectRemifentanilen_US
dc.subjectSuccinylcholineen_US
dc.subjectIntubationen_US
dc.titleRemifentanil without muscle relaxants for intubation in microlaryngoscopy: a double blind randomised clinical trialen_US
dc.typeArticleen_US

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