Metabolic changes in pelvic lesions: Findings at proton MR spectroscopic imaging

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dc.authorwosidSaraç, Kaya/ABI-1091-2020
dc.contributor.authorHascalik, S
dc.contributor.authorCelik, O
dc.contributor.authorSarac, K
dc.contributor.authorMeydanli, MM
dc.contributor.authorAlkan, A
dc.contributor.authorMizrak, B
dc.date.accessioned2024-08-04T20:15:03Z
dc.date.available2024-08-04T20:15:03Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The purpose of this study is to investigate the in vivo magnetic resonance spectroscopic (MRS) features of pelvic lesions using long echo time and to characterize the spectral patterns of various pathological entities. Materials and Methods: 17 patients with surgically and histopathologically confirmed pelvic lesions underwent long echo-time MRS, and the results obtained were analyzed. Before laparotomy, choline (Cho), lactate, lipid and creatine (Cr) levels of all lesions were measured by single voxel MRS ( point-resolved spectroscopy technique, TE 136 ms). Voxels were placed in the center of the lesions. The MRS results of lesions were compared with the final histopathological diagnoses. Results: Spectroscopy analysis of serous, mucinous and undifferentiated carcinoma of the ovary revealed Cho, lactate and lipid signals, but granulosa-theca cell tumor showed only a lipid signal. The Cho signal was obtained from only 3 patients with mature cystic teratoma but none of the other benign ovarian tumors and pelvic abscesses. A lipid signal was detected in 3 patients diagnosed with pelvic abscess and all benign ovarian tumors. In addition to the lipid signal, a lactate signal was detected in the spectra of two pelvic abscesses. One case of endometrioma and 1 case of teratoma did not show any signal. Conclusion: MRS demonstrates significant differences in metabolite concentration between benign and malignant ovarian tumors and pelvic abscesses. MRS may therefore be helpful in the differential diagnosis of adnexal lesions. Copyright (C) 2005 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000086003
dc.identifier.endpage127en_US
dc.identifier.issn0378-7346
dc.identifier.issue3en_US
dc.identifier.pmid15920339en_US
dc.identifier.scopus2-s2.0-26444447124en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage121en_US
dc.identifier.urihttps://doi.org/10.1159/000086003
dc.identifier.urihttps://hdl.handle.net/11616/94136
dc.identifier.volume60en_US
dc.identifier.wosWOS:000232490400001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofGynecologic and Obstetric Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpelvic tumoren_US
dc.subjectpelvic abscessen_US
dc.subjectmagnetic resonance spectroscopyen_US
dc.titleMetabolic changes in pelvic lesions: Findings at proton MR spectroscopic imagingen_US
dc.typeArticleen_US

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