Auditory event-related potentials in patients with premature ejaculation

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dc.authoridozcan, abdulcemal/0000-0002-6759-7556;
dc.authorwosidozcan, abdulcemal/B-1348-2008
dc.authorwosidSoylu, Ahmet/P-2015-2019
dc.contributor.authorOzcan, C
dc.contributor.authorOzbek, E
dc.contributor.authorSoylu, A
dc.contributor.authorYilmaz, U
dc.contributor.authorGuzelipek, M
dc.contributor.authorBalbay, MD
dc.date.accessioned2024-08-04T20:12:18Z
dc.date.available2024-08-04T20:12:18Z
dc.date.issued2001
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives. To investigate in a descriptive manner the P300 component of the event-related potential (ERP), which is related to aspects of cognitive processing, in patients with premature ejaculation (PE) to determine whether there is a cognitive alteration in this condition. Recent studies with short latency evoked potentials such as cortical somatosensory evoked potentials have indicated that afferent sensory inputs from the genital area to the nervous system are increased in PE, However, the cortical neural process of ejaculation has remained poorly understood. Methods. We performed ERPs in 20 patients with PE and in 20 age-matched healthy subjects. ERPs were evoked by an auditory oddball paradigm consisting of 150 tone bursts (80% 1 kHz; 20% 2 kHz). The latencies of the N200 and the P300 waves and the amplitude of the P300 wave were measured. Results. The mean latencies of the N200 and P300 waves were significantly longer in the patients with PE than in the controls (P<0.04 and <0.03, respectively). No significant difference was found in the P300 amplitude between the controls and patients (P>0.05). Conclusions. These data indicate that the greater cortical representation of sensory stimuli from the genital areas that has been shown with somatosensory evoked potential studies might be related to a cognitive/neurobehavioral dysfunction. The dysfunction involves an increased time to evaluate and categorize the stimuli in the central nervous system, with no change in the quality of cognition and neural disinhibition by the prefrontal cortex to early sensory processing in subcortical or primary cortical regions, which are cognitive neural processes underlying ERP generation. UROLOGY 58: 1025-1029, 2001 (C) 2001, Elsevier Science Inc.en_US
dc.identifier.doi10.1016/S0090-4295(01)01428-5
dc.identifier.endpage1029en_US
dc.identifier.issn0090-4295
dc.identifier.issn1527-9995
dc.identifier.issue6en_US
dc.identifier.pmid11744481en_US
dc.identifier.scopus2-s2.0-0035663952en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1025en_US
dc.identifier.urihttps://doi.org/10.1016/S0090-4295(01)01428-5
dc.identifier.urihttps://hdl.handle.net/11616/93347
dc.identifier.volume58en_US
dc.identifier.wosWOS:000172752200041en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofUrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPenile Sensitivityen_US
dc.subjectPrefrontal Cortexen_US
dc.subjectP300en_US
dc.subjectAnxietyen_US
dc.titleAuditory event-related potentials in patients with premature ejaculationen_US
dc.typeArticleen_US

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