Neonatal cholestasis: Retrospective analysis of 94 cases

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dc.authorscopusid57203099431
dc.authorscopusid7003301157
dc.authorscopusid57190758124
dc.authorscopusid55391570100
dc.authorscopusid35562819000
dc.contributor.authorBıçakcıoğlu I.
dc.contributor.authorÖzdemir R.
dc.contributor.authorTurgut H.
dc.contributor.authorGökçe I.K.
dc.contributor.authorSelimoğlu M.A.
dc.date.accessioned2024-08-04T19:59:06Z
dc.date.available2024-08-04T19:59:06Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractNeonatal cholestasis is a condition that begins in the neonatal period due to intrahepatic and the extrahepatic causes. The objective of our study was to evaluate the ethiological factors, symptoms and physical examination findings, laboratory results and follow up results for cases with neonatal cholastasis and to compare this data with those of other studies. Neonatal cholestasis cases that were diagnosed between 2009-2014 in Neonatal Care Unit were included in this study. The diagnoses, physical examinations, clinical courses and the prognoses were retrospectively evaluated in two groups; younger than 32 weeks (Group 1) and older than 32 weeks (Group 2). 94 newborns were found to have neonatal cholestasis. Patients in Group 2 (n= 60) had earlier neonatal cholestasis (p=0.001). The most common complaints of the patients and/or physical examination findings were jaundice. The most common etiologic factors involved in the etiology of neonatal cholestasis were TPN associated cholestasis (n= 21). No etiology was defiend in 13 patients. It was observed that 33 (35%) of the patients died during the follow-up. We consider that the early diagnosis is important; during the search of the etiological cause, the features such as the gestational age and the birth weight of the patient should be taken into consideration and we also consider that when the extrahepatic causes are relevant, the surgical treatment should not be delayed. © 2018 Cocuk Sagligi ve Hastaliklan Dergisi. All rights reserved.en_US
dc.identifier.endpage138en_US
dc.identifier.issn0010-0161
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85050495677en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage129en_US
dc.identifier.urihttps://hdl.handle.net/11616/90381
dc.identifier.volume60en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherCocuk Sagligi ve Hastaliklan Dergisien_US
dc.relation.ispartofCocuk Sagligi ve Hastaliklari Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectJaundiceen_US
dc.subjectNeonatal cholestasisen_US
dc.subjectNewbornen_US
dc.titleNeonatal cholestasis: Retrospective analysis of 94 casesen_US
dc.title.alternativeNeonatal kolestaz: 94 olgunun geriye dönük incelenmesien_US
dc.typeArticleen_US

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