A Case of Rickettsiosis in a non-Endemic Region
Küçük Resim Yok
Tarih
2025
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bilimsel Tip Yayinevi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Mediterranean spotted fever (MSF) is an acute, febrile rickettsiosis caused by Rickettsia conorii, which is endemic in Africa, Mediterranean countries, and Turkiye, with most reported cases originating from the Marmara region. This case presents a patient from a non-endemic region who was hospitalized with a preliminary diagnosis of Crimean-Congo Hemorrhagic Fever (CCHF) after experiencing a tick bite, followed by fever, rash, and headache, and was subsequently diagnosed with MSF. The patient initially presented to the emergency department with a tick attached to the distal posterolateral area of the left thigh. The tick was removed, and the patient was discharged. Approximately ten days later, they returned with joint pain, headache, weakness, and fever. Initially suspected of CCHF, the examination revealed widespread maculopapular rashes and petechiae, along with a hyperemic lesion at the tick attachment site. Laboratory tests ruled out CCHF, with negative PCR and IgM results. Due to persistent symptoms, R. conorii IgM and IgG tests were ordered, and empirical treatment with doxycycline (2 x 100 mg/day PO) was initiated. A fever response was observed by the second day of Rickettsia treatment, with indirect immunofluorescence antibody tests confirming R. conorii IgM (1/384) and IgG (1/1280) positivity. After completing a full ten-day course of doxycycline, the patient was discharged. This case underscores the importance of considering rickettsiosis in the differential diagnosis of fever and rash following tick exposure, even in non-endemic regions, and aims to raise awareness through its publication in the literature.
Açıklama
Anahtar Kelimeler
Rickettsia, Fever, Tick, Rash
Kaynak
Flora Infeksiyon Hastaliklari Ve Klinik Mikrobiyoloji Dergisi
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
30
Sayı
2
