Nobel's harvest in Turkiye: Delving into Artemisia's spirit - essential oil content and antimicrobial potential of seven species

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dc.contributor.authorOsmanlioglu-Dag, Suheda Rumeysa
dc.contributor.authorOzturk, Gozde
dc.contributor.authorCankaya, Iffet Irem
dc.contributor.authorKursat, Murat
dc.contributor.authorDemirci, Betul
dc.contributor.authorOzkan, Ayse Mine GENcLER
dc.date.accessioned2026-04-04T13:31:20Z
dc.date.available2026-04-04T13:31:20Z
dc.date.issued2024
dc.departmentİnönü Üniversitesi
dc.description.abstractThe 2015 Nobel Prize in Physiology or Medicine was awarded due to the isolation of the active ingredient of artemisinin, a sesquiterpene lactone, from the plant Artemisia annua L. and proving its effectiveness in the treatment of malaria, and the chemical contents and biological activities of other Artemisia L. species aroused great interest. In this study, it was aimed to investigate the chemical content of essential oils obtained by hydrodistillation from the aerial parts of seven Artemisia species (A. abrotanum L., A. absinthium L., A. annua L., A. austriaca Jacq., A. chamaemelifolia Vill., A. incana (L.) Druce, A. tournefortiana Rchb.) growing in different regions of Turkiye and to evaluate their antimicrobial activities. The essential oils were analyzed by GC and GC-MS. The main components are chrysanthenone (55.9%) for A. abrotanum, sabinyl acetate (23.0%) for A. absinthium, artemisia ketone (53.7%) for A. annua, camphor (34.2%) for A. austriaca, selin-11-en-4-alpha-ol (29.1%) for A. chamaemelifolia, camphor (29.7%) for A. incana, and (Z)-beta-farnesene (71.5%) for A. tournefortiana. In vitro antimicrobial activity of essential oils against five microorganisms (Bacillus subtilis, Escherichia coli, Salmonella typhimurium, Staphylococcus aureus, Pseudomonas aeruginosa) was investigated using the microdilution method. The highest activity against all species was observed in A. incana essential oil. Staphylococcus aureus was found to be the most sensitive bacteria to all essential oils.
dc.description.sponsorshipAnkara University, Turkiye [21L0237011]
dc.description.sponsorshipThis research has financially supported by Scientific Research Projects (BAP) (no. 21L0237011) , Ankara University, Turkiye and produced from PhD thesis 'Pharmaceutical Botanical investigetions on some Artemisia L. (Asteraceae) species that grow in Turkey'.
dc.identifier.doi10.29228/jrp.866
dc.identifier.endpage1945
dc.identifier.issn2630-6344
dc.identifier.issue6
dc.identifier.scopus2-s2.0-85213032268
dc.identifier.scopusqualityN/A
dc.identifier.startpage1936
dc.identifier.urihttps://doi.org/10.29228/jrp.866
dc.identifier.urihttps://hdl.handle.net/11616/108745
dc.identifier.volume28
dc.identifier.wosWOS:001407427700008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherMarmara Univ, Fac Pharmacy
dc.relation.ispartofJournal of Research in Pharmacy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250329
dc.subjectAntimicrobial
dc.subjectArtemisia
dc.subjectessential oil
dc.subjectGC
dc.subjectGC-MS.
dc.titleNobel's harvest in Turkiye: Delving into Artemisia's spirit - essential oil content and antimicrobial potential of seven species
dc.typeArticle

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