The effects of acute hypoxia on audition:An experimental study

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dc.contributor.authorÇiçek, M. T.
dc.contributor.authorKoca Fırat, Çiğdem
dc.contributor.authorAkarçay, Mustafa
dc.date.accessioned2022-02-08T08:50:37Z
dc.date.available2022-02-08T08:50:37Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAbstract: OBJECTIVE: Obstructive sleep apnea syndrome (OSAS) is a health problem that has increasing importance in society. In the literature, many studies about an audition in patients with OSAS are present. In this study, the effects of hypoxia on an audition that develop during the apnea attacks in OSAS were investigated experimentally.METHODS: This study was conducted in Inonu University Audiology Laboratory after the approval of Inonu University Faculty of Medicine Experimental Animal Research Ethics Committee (Protocol Number: 2011/A-102). In this study, 15 Wistar albino rats with a weight of 250–300 g were used. Anesthesia was performed by 40 mg/kg Ketamine and 5 mg/kg Xylazine through intramuscular administration. The processes were applied in the silence. This study involved 15 rats with normal auditory functions. Only tracheotomy was performed in the control group. Auditory assays were administered with otoacoustic emis-sion (DP gram) before and after the process. In hypoxia group, hypoxia was created by making apnea attacks that lasted at least 10 seconds after the tracheotomy process. Auditory assays using DP gram were performed before tracheotomy and during hypoxia in the hypoxia group.RESULTS: In the control group, statistically significant values were not found. In the hypoxia group, statistically significant differences were detected in high frequencies.CONCLUSION: In conclusion, cochlear reply decreased in high frequencies during hypoxia that was created by apnea attacks.en_US
dc.identifier.citationÇİÇEK M. T,KOCA Ç. F,AKARCAY M (2021). The effects of acute hypoxia on audition:An experimental study. İstanbul Kuzey Klinikleri, 8(1), 1 - 7. Doi: 10.14744/nci.2020.10586en_US
dc.identifier.doi10.14744/nci.2020.10586en_US
dc.identifier.endpage7en_US
dc.identifier.issn2148-4902
dc.identifier.issn2536-4553
dc.identifier.issue1en_US
dc.identifier.pmid33623866en_US
dc.identifier.startpage1en_US
dc.identifier.trdizinid424317en_US
dc.identifier.urihttps://doi.org/10.14744/nci.2020.10586
dc.identifier.urihttps://hdl.handle.net/11616/46826
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/424317
dc.identifier.volume8en_US
dc.identifier.wosWOS:000619599000001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofİstanbul Kuzey Kliniklerien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe effects of acute hypoxia on audition:An experimental studyen_US
dc.typeArticleen_US

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