Characterization of a cDNA from Beta maritima that confers nickel tolerance in yeast

Basit Öğe Kaydı
dc.authorid110769en_US
dc.contributor.authorKoç, Ahmet
dc.contributor.authorBozdağ, Gönensin O.
dc.contributor.authorKaya, Alaattin
dc.contributor.authorKoç, Ahmet
dc.contributor.authorNoll, Gündüla A.
dc.date.accessioned2017-06-06T06:47:11Z
dc.date.available2017-06-06T06:47:11Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.descriptionGene 538 (2014) 251–257en_US
dc.description.abstractNickel is an essential micronutrient due to its involvement in many enzymatic reactions as a cofactor. However, excess of this element is toxic to biological systems. Here, we constructed a cDNA library from Beta maritima and screened it in the yeast system to identify genes that confer resistance to toxic levels of nickel. A cDNA clone (NIC6), which encodes for a putative membrane protein with unknown function, was found to help yeast cells to tolerate toxic levels of nickel. A GFP fused form of Nic6 protein was localized to multivesicular structures in tobacco epidermal cells. Thus, our results suggest a possible role of Nic6 in nickel and intracellular ion homeostasis.en_US
dc.identifier.citationBozdag Gonensin O., Kaya Alaattin, Koc Ahmet, Noll Gundula A., Prüfer Dirk, Karakaya Hüseyin Caglar (2014). Characterization of a DNA from Beta maritima that confers nickel tolerance in yeast. Gene. 2014 Apr 1;538(2):251-7.en_US
dc.identifier.doi10.1016/j.gene.2014.01.052en_US
dc.identifier.endpage0en_US
dc.identifier.issue0en_US
dc.identifier.startpage0en_US
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pubmed/24487090
dc.identifier.urihttps://hdl.handle.net/11616/7052
dc.identifier.volume0en_US
dc.language.isoenen_US
dc.publisherGeneen_US
dc.relation.ispartofGeneen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNickelen_US
dc.subjectBeta maritimaen_US
dc.subjectYeasten_US
dc.subjectTransporter proteinen_US
dc.subjectLon homeostasisen_US
dc.subjectHeavy metal toxicityen_US
dc.titleCharacterization of a cDNA from Beta maritima that confers nickel tolerance in yeasten_US
dc.typeArticleen_US

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