Effect of Vitamin D Deficiency on Contrast Sensitivity Function

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dc.authoridOzturk, Emrah/0000-0002-3590-3213
dc.authoridcankaya, cem/0000-0002-7716-0438
dc.authorwosidÖztürk, Emrah/H-5241-2017
dc.authorwosidCankaya, Cem/HTR-3803-2023
dc.contributor.authorOzturk, Emrah
dc.contributor.authorCankaya, Cem
dc.date.accessioned2024-08-04T20:47:28Z
dc.date.available2024-08-04T20:47:28Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose The purpose of this study is to investigate the effects of vitamin D (vit D) deficiency on contrast sensitivity (CS) function and retinal layers. Materials and methods Group 1 consisted of 42 patients aged between 18 and 50 years with vit D deficiency and Group 2 consisted of sex- and age-matched 34 healthy subjects with normal vit D levels. Functional acuity contrast testing (FACT) was performed using the Optec 6500 vision testing system. The average retinal nerve fiber layer (RNFL) thickness and macular thickness (MT) obtained from nine macular areas in the Early Treatment Diabetic Retinopathy Study were evaluated using SD-OCT (RS-3000; Nidek Inc., Fremont, CA, USA) following a detailed ophthalmologic examination. Measurements were performed on both eyes. Results A lower CS was found in Group 1 compared to Group 2 in all spatial frequencies. A statistically significant difference was observed between the groups in 6, 12 and 18 cpd spatial frequencies, respectively. (p = .004, p = .001, p = .042, respectively). There was no statistically significant difference between groups in terms of RNFL thicknesses (p = .200). There was an increase in MT in Group 1. However, this increase was statistically significant in the inferior inner area in the right eye, and in the inferior inner, temporal inner and outer macular areas in the left eye (p = .018, p = .003, p = .033, p = .040, respectively). Conclusion It was observed that vit D deficiency had negative effects on CS function and also caused thickness difference in certain segments of retinal layers.en_US
dc.identifier.doi10.1080/02713683.2020.1781194
dc.identifier.endpage1624en_US
dc.identifier.issn0271-3683
dc.identifier.issn1460-2202
dc.identifier.issue12en_US
dc.identifier.pmid32552162en_US
dc.identifier.scopus2-s2.0-85087430883en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1619en_US
dc.identifier.urihttps://doi.org/10.1080/02713683.2020.1781194
dc.identifier.urihttps://hdl.handle.net/11616/99394
dc.identifier.volume45en_US
dc.identifier.wosWOS:000597376100020en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofCurrent Eye Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectContrast sensitivityen_US
dc.subjectvisual functionen_US
dc.subjectvitamin D deficiencyen_US
dc.subjectretinal nerve fiber layeren_US
dc.subjectmacular thicknessen_US
dc.titleEffect of Vitamin D Deficiency on Contrast Sensitivity Functionen_US
dc.typeArticleen_US

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