Management of extravasation injuries: A retrospective study

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dc.authorwosidFirat, Cemal/D-1292-2012
dc.contributor.authorFirat, Cemal
dc.contributor.authorErbatur, Serkan
dc.contributor.authorAytekin, Ahmet Hamdi
dc.date.accessioned2024-08-04T20:37:23Z
dc.date.available2024-08-04T20:37:23Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe extravasation of many agents during administration by way of the peripheral veins can produce severe necrosis of the skin and subcutaneous tissue. The incidence of an extravasation injury is elevated in the populations prone to complications, including the younger age groups. The severity of the necrosis depends on properties of the extravasated agent (vinca alkaloids, antracyclines, catecholamines, cationic solutions, osmotically active chemicals) including the type, concentration, and the quantity injected. In general, the primary diseases were chronic diseases such as hepatic or ischaemic encephalopathies, cardiac or pulmonary diseases, diabetes mellitus, and oncological diseases. The aim of this article was to explore the prevention, diagnosis, and treatment of extravasation injuries with a review of the literature. From January 2009 to August 2011, 22 patients were reviewed. Ten patients were children, and the others were adults. The surgical interventions were delayed until the development of the necrosis. A topical boric acid 3% solution was applied to all wounds with repetitive debridement. Debridement was performed once every 2 days and was continued until healthy tissue was obtained. The wounds of eight patients were repaired with split-thickness skin grafts, the wounds of six patients were reconstructed with randomised fasciocutaneous flaps, and the wounds of five patients healed by secondary intention. The wounds of three patients with massive swelling of the forearms were treated with only conservative modalities and limb elevation for 24-48 hours. Boric acid was found to promote granulation tissue in the wounds. The extravasation injuries can be prevented by using appropriate measures, such as the avoidance of perfusion under pressure, patient participation in pain follow-up, wound management by experienced health professionals, and preference for large and suitable veins.en_US
dc.description.sponsorshipinstitutional ethics committee [2011/98]en_US
dc.description.sponsorshipThe authors have no financial or proprietary interest in any instrument or product used in this study. The project was approved by the institutional ethics committee (05.07.2011, 2011/98).en_US
dc.identifier.doi10.3109/2000656X.2012.741065
dc.identifier.endpage65en_US
dc.identifier.issn2000-656X
dc.identifier.issue1en_US
dc.identifier.pmid23190022en_US
dc.identifier.scopus2-s2.0-84872694687en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage60en_US
dc.identifier.urihttps://doi.org/10.3109/2000656X.2012.741065
dc.identifier.urihttps://hdl.handle.net/11616/95928
dc.identifier.volume47en_US
dc.identifier.wosWOS:000313681700010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInforma Healthcareen_US
dc.relation.ispartofJournal of Plastic Surgery and Hand Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectExtravasation injuriesen_US
dc.subjectextravasation managementen_US
dc.subjectpreventionen_US
dc.subjectboric aciden_US
dc.titleManagement of extravasation injuries: A retrospective studyen_US
dc.typeArticleen_US

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