Frequency of sublingual nitroglycerin prescription in patients with coronary artery disease and angina and awareness of patients about the shelf life of the drug

dc.authoridYılmaz, Ömer Çağlar/0000-0001-5245-5216
dc.authorwosidÇUĞLAN, bilal/AAP-8878-2021
dc.authorwosidYılmaz, Ömer Çağlar/ABB-6582-2020
dc.contributor.authorYilmaz, Omer Caglar
dc.contributor.authorKeskin, Gokhan
dc.contributor.authorCuglan, Bilal
dc.contributor.authorSelcoki, Yusuf
dc.contributor.authorTemizkan, Ayla
dc.contributor.authorEryonucu, Beyhan
dc.contributor.authorSoran, Ozlem
dc.date.accessioned2024-08-04T20:35:42Z
dc.date.available2024-08-04T20:35:42Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: ACC/AHA/ESC guidelines recommend sublingual nitroglycerin (SNG) in patients with stable angina pectoris and coronary artery disease (CAD). However, the shelf life of SNG following first use is six months for SNG tablets and two years for SNG sprays. We investigated the frequency of prescription of SNG tablets/sprays in patients having anginal symptoms and documented CAD and the awareness levels of patients about appropriate use of SNG. Study design: Three hundred patients (201 men, 99 women; mean age 61.7 +/- 10.8 years) with documented CAD and angina were enrolled into this study. Angina pectoris was categorized according to the functional classification system of the Canadian Cardiovascular Society. Data on cardiovascular past histories, risk factors, medications, and the use of SNG were recorded. Results: At least one risk factor was present in 96% of the patients. Only 46% of the patients had a prescription for SNG. Of those with a prescription of SNG tablet and spray, 91.8% and 84.4% did not know the shelf life of the product, respectively. Of those who were routinely carrying SNG, 35.6% had an expired product. Of those with a prescription of SNG, only 65.9% were informed by the physician on the proper use of SNG. Conclusion: Our results show that, despite recommendations of the guidelines, SNG is not prescribed to a substantial percentage of patients with CAD and angina, a considerable fraction of patients carry an expired product, and that patients are not adequately informed by the physicians on the use of SNG. These problems will certainly affect the optimal medical management of CAD and its efficacy.en_US
dc.identifier.doi10.5543/tkda.2011.01635
dc.identifier.endpage473en_US
dc.identifier.issn1016-5169
dc.identifier.issn1308-4488
dc.identifier.issue6en_US
dc.identifier.pmid21918316en_US
dc.identifier.scopus2-s2.0-84855180711en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage469en_US
dc.identifier.urihttps://doi.org/10.5543/tkda.2011.01635
dc.identifier.urihttps://hdl.handle.net/11616/95524
dc.identifier.volume39en_US
dc.identifier.wosWOS:000421533600004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherKare Publen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of The Turkish Society of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAngina pectoris/drug therapyen_US
dc.subjectcoronary artery diseaseen_US
dc.subjectnitroglycerin/therapeutic useen_US
dc.subjectpractice guidelines as topicen_US
dc.subjectvasodilator agentsen_US
dc.titleFrequency of sublingual nitroglycerin prescription in patients with coronary artery disease and angina and awareness of patients about the shelf life of the drugen_US
dc.typeArticleen_US

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