Importance of proper diagnosis for management: multifocal choroiditis mimicking ocular histoplasmosis syndrome

dc.authoridturkcuoglu, peykan/0000-0002-9750-6213
dc.authorwosidturkcuoglu, peykan/GQB-2596-2022
dc.authorwosidC, R/HJA-9099-2022
dc.authorwosidC, Roomasa/AAK-5176-2020
dc.authorwosidNguyen, Quan/JMP-5630-2023
dc.authorwosidNguyen, Truong/JXN-9786-2024
dc.contributor.authorHatef, Elham
dc.contributor.authorTurkcuoglu, Peykan
dc.contributor.authorIbrahim, Mohamed
dc.contributor.authorSepah, Yasir
dc.contributor.authorShulman, Matthew
dc.contributor.authorHeo, Jangwon
dc.contributor.authorLee, Jeong Hee
dc.date.accessioned2024-08-04T20:36:00Z
dc.date.available2024-08-04T20:36:00Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose The study aims to evaluate a series of patients with initial diagnosis of ocular histoplasmosis syndrome (OHS) with progression and response to treatments consistent with multifocal choroiditis (MFC). Methods Retrospective review of nine patients referred for management of recurrent OHS lesions. Serology panel was conducted to rule out autoimmune and infectious causes. Results Clinical examination revealed multiple small, punched-out peripheral chorioretinal scars, and peripapillary atrophy. Histoplasma antigen/antibody was negative in all patients. Fluorescein angiography and optical coherence tomography confirmed active inflammation in five patients. Immunomodulatory therapy (IMT) was initiated to control active inflammation. While on IMT, visual acuity stabilized or improved in three patients with no recurrence of CNVor lesion activities over the follow-up period. Conclusions MFC may initially masquerade as OHS. Clinical characteristics of recurrent MFC and absence of histoplasma titer may lead to consideration of IMT and other proper treatments for MFC.en_US
dc.identifier.doi10.1007/s12348-010-0016-4
dc.identifier.endpage63en_US
dc.identifier.issn1869-5760
dc.identifier.pmid21484182en_US
dc.identifier.scopus2-s2.0-84863005931en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage55en_US
dc.identifier.urihttps://doi.org/10.1007/s12348-010-0016-4
dc.identifier.urihttps://hdl.handle.net/11616/95703
dc.identifier.volume1en_US
dc.identifier.wosWOS:000215780900010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofJournal of Ophthalmic Inflammation and Infectionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMultifocal choroiditisen_US
dc.subjectOcular histoplasmosis syndromeen_US
dc.titleImportance of proper diagnosis for management: multifocal choroiditis mimicking ocular histoplasmosis syndromeen_US
dc.typeArticleen_US

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