Investigation of the relationship between inflammatory blood parameters and rosacea and demodex infestation

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dc.authoridTürkmen, Dursun/0000-0001-9076-4669
dc.authoridAltunisik, Nihal/0000-0001-6844-1097
dc.authorwosidSener, Serpil/ABI-6229-2020
dc.authorwosidTürkmen, Dursun/ABG-3801-2020
dc.authorwosidAltunisik, Nihal/ABG-8567-2020
dc.contributor.authorAltunisik, Nihal
dc.contributor.authorTurkmen, Dursun
dc.contributor.authorSener, Serpil
dc.date.accessioned2024-08-04T20:47:02Z
dc.date.available2024-08-04T20:47:02Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground Rosacea is a chronic inflammatory disease. Although the etiopathogenesis of the disease has not been established, it is known that inflammation plays a prominent role in the disease. Demodex mites have been thought to have a role in the pathogenesis of rosacea by causing the occurrence of inflammatory lesions. In the literature, many studies have reported that complete blood count (CBC) parameters have been used as diagnostic biomarkers in diseases associated with inflammatory process. Aims The aim of this study was to evaluate CBC parameters in rosaceous patients with and without demodex mite and to compare with healthy controls (HCs). Patients/Methods Ninety patients followed in our clinic between January and October 2019 and 62 healthy controls matching in terms of age and sex were included in the study. CBC parameters of the patients and the HCs were compared, retrospectively. Results There was no statistically significant difference in mean platelet volume (MPV), red cell distribution width (RDW), neutrophil lymphocyte ratio, monocyte lymphocyte ratio, and platelet lymphocyte ratio levels between all patients and HCs. RDW values were significantly lower in demodex (+) rosace group, when compared to demodex (-) rosace group and HCs. Conclusions The lower RDW levels in the demodex (+) group suggested that demodex mite did not have an increasing effect on inflammation and was effective in the disease through alternative pathways.en_US
dc.identifier.doi10.1111/jocd.13254
dc.identifier.endpage2108en_US
dc.identifier.issn1473-2130
dc.identifier.issn1473-2165
dc.identifier.issue8en_US
dc.identifier.pmid31840349en_US
dc.identifier.scopus2-s2.0-85076785541en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2105en_US
dc.identifier.urihttps://doi.org/10.1111/jocd.13254
dc.identifier.urihttps://hdl.handle.net/11616/99109
dc.identifier.volume19en_US
dc.identifier.wosWOS:000502705500001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Cosmetic Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdemodexen_US
dc.subjectinflammatory blood parametersen_US
dc.subjectred cell distribution widthen_US
dc.subjectrosaceaen_US
dc.titleInvestigation of the relationship between inflammatory blood parameters and rosacea and demodex infestationen_US
dc.typeArticleen_US

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