Chondroradionecrosis in two patients with laryngeal carcinoma

dc.authorid7028en_US
dc.contributor.authorFırat, Yezdan
dc.contributor.authorKızılay, Ahmet
dc.contributor.authorFırat, Ahmet Kemal
dc.contributor.authorSerin, M.
dc.contributor.authorErkal, H.S.
dc.date.accessioned2017-06-02T13:18:26Z
dc.date.available2017-06-02T13:18:26Z
dc.date.issued2007
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPostradiotherapy necrosis in the larynx is a rare but serious complication. It must be differentiated from tumor recurrence with radiological and histopathological studies. Herein, we presented two patients with stage II and stage IV larynx carcinoma who developed chondroradionecrosis following radiotherapy. The first patient did not accept surgical treatment and was treated with curative radiotherapy at a dose of 70 Gy. The other one received adjuvant radiotherapy at a dose of 46 Gy following total laryngectomy and bilateral functional neck dissection. The two patients were evaluated with computed tomography and magnetic resonance imaging, respectively. Pathologic examination of multiple biopsies taken from both cases showed coagulation necrosis without malignancy. The first patient had grade IV radionecrosis according to the Chandler classification and underwent total laryngectomy because of non-functional larynx. Histopathologically, there were no malignant cells, but widespread fibrosis and coagulation necrosis. The other patient was treated with conservative treatment and local debridement.en_US
dc.identifier.citationFırat, Y. Kızılay, A. Fırat, A. K. Serin, M. Erkal, H.S. (2007). Chondroradionecrosis in two patients with laryngeal carcinoma. Kulak Burun Boğaz İhtisas Dergisi. 17(4):242-248.en_US
dc.identifier.endpage248en_US
dc.identifier.issue4en_US
dc.identifier.startpage242en_US
dc.identifier.urihttps://hdl.handle.net/11616/7020
dc.identifier.volume17en_US
dc.language.isoenen_US
dc.publisherKulak Burun Boğaz İhtisas Dergisien_US
dc.relation.ispartofKulak Burun Boğaz İhtisas Dergisien_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.titleChondroradionecrosis in two patients with laryngeal carcinomaen_US
dc.typeArticleen_US

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