Maternal and fetal plasma adenosine deaminase, xanthine oxidase and malondialdehyde levels in pre-eclampsia

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dc.authoridbay karabulut, aysun/0000-0002-7873-2805
dc.authorwosidbay karabulut, aysun/HJP-0995-2023
dc.contributor.authorKarabulut, AB
dc.contributor.authorKafkasli, A
dc.contributor.authorBurak, F
dc.contributor.authorGozukara, EM
dc.date.accessioned2024-08-04T20:14:52Z
dc.date.available2024-08-04T20:14:52Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate maternal-fetal plasma adenosine deaminase, xanthine oxidase (ADA, XO) activity and malondialdehyde (MDA) levels and the relationship between them in pre-eclampsia. Maternal and umbilical cord whole blood samples were taken from 29 pre-eclamptic and 33 normal pregnants. The plasma ADA, XO activities as well as MDA levels were assayed by spectrophotometric methods. MDA levels and ADA, XO activities were found to be higher in maternal and fetal plasma in pre-eclamptics than in normal pregnancy. The differences were statistically significant between groups (p < 0.05). Increased maternal-fetal plasma XO and ADA activities, its a marker of immunological disorder, may be related to the pathogenesis of pre-eclampsia. In addition, increased MDA levels may be a reflection of increased oxidative stress in pre-eclamptics and their fetuses. Copyright (c) 2004 John Wiley & Sons, Ltd.en_US
dc.identifier.doi10.1002/cbf.1152
dc.identifier.endpage283en_US
dc.identifier.issn0263-6484
dc.identifier.issn1099-0844
dc.identifier.issue4en_US
dc.identifier.pmid15515122en_US
dc.identifier.scopus2-s2.0-22244433854en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage279en_US
dc.identifier.urihttps://doi.org/10.1002/cbf.1152
dc.identifier.urihttps://hdl.handle.net/11616/94005
dc.identifier.volume23en_US
dc.identifier.wosWOS:000230507700008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofCell Biochemistry and Functionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpre-eclampsiaen_US
dc.subjectadenosine deaminaseen_US
dc.subjectxanthine oxidaseen_US
dc.subjectmalondialdehydeen_US
dc.titleMaternal and fetal plasma adenosine deaminase, xanthine oxidase and malondialdehyde levels in pre-eclampsiaen_US
dc.typeArticleen_US

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