Corneal endothelial changes in patients with vitamin D deficiency

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dc.authoridGündüz, Abuzer/0000-0003-1752-6810
dc.authoridcankaya, cem/0000-0002-7716-0438
dc.authorwosidGündüz, Abuzer/HLH-2417-2023
dc.authorwosidCankaya, Cem/HTR-3803-2023
dc.authorwosidcankaya, cem/ABH-6458-2020
dc.contributor.authorCankaya, Cem
dc.contributor.authorCumurcu, Tongabay
dc.contributor.authorGunduz, Abuzer
dc.date.accessioned2024-08-04T20:45:23Z
dc.date.available2024-08-04T20:45:23Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: The purpose of this study is to evaluate the effect of vitamin D deficiency on corneal endothelial layer using specular microscopy. Methods: Fifty-eight eyes of 58 patients whose vitamin 13 level was below 15 ng/ml and who had no ocular pathology were included in the study (Group 1). Forty eyes of 40 age-and sex-matched subjects were enrolled as control group (Group 2). Corneal endothelial cell density (CD), coefficient of variation (CV), hexagonal cell ratio (HEX), and central corneal thickness (CCT) were measured using specular microscopy (Konan Medical Inc., Nishinomiya, Japan). The obtained data were compared between the groups. Results: There was no significant difference between the groups in terms of age and gender (P = 0.344, P = 0.399, respectively). The mean CD value was 2772.79 +/- 202.21 cells/mm(2) in Group 1 and 2954.97 +/- 116.89 cells/mm(2) in Group 2 (P = 0.001). The mean CV value was 30.31 +/- 3.65 in Group 1 and 28.20 +/- 2.71 in Group 2 (P = 0.003). The mean HEX value was 46.56 +/- 6.32 in Group 1 and 51.07 +/- 5.28 in Group 2 (P = 0.001). The mean CCT value was 555.87 +/- 36.90 mu in group 1 and 549.0 +/- 37.39 mu in Group 2 (P = 0.96). Conclusion: Vitamin D deficiency may affect the corneal endothelial layer. Patients with vitamin D deficiency should be evaluated for endothelial parameters in particular before an intraocular surgery. Further studies are needed to confirm our results.en_US
dc.identifier.doi10.4103/ijo.IJO_238_18
dc.identifier.endpage1261en_US
dc.identifier.issn0301-4738
dc.identifier.issn1998-3689
dc.identifier.issue9en_US
dc.identifier.pmid30127135en_US
dc.identifier.scopus2-s2.0-85052711670en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1256en_US
dc.identifier.urihttps://doi.org/10.4103/ijo.IJO_238_18
dc.identifier.urihttps://hdl.handle.net/11616/98454
dc.identifier.volume66en_US
dc.identifier.wosWOS:000442780400005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofIndian Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCorneaen_US
dc.subjectcorneal endothelial layeren_US
dc.subjectspecular microscopyen_US
dc.subjectvitamin D deficiencyen_US
dc.titleCorneal endothelial changes in patients with vitamin D deficiencyen_US
dc.typeArticleen_US

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