Can High Average Oxygen Saturation be a Risk Factor for Necrotizing Enterocolitis in VLBW Infants?

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dc.authoridOGUZ, SUNA SERIFE/0000-0002-1870-0983;
dc.authorwosidOGUZ, SUNA SERIFE/GWZ-7382-2022
dc.authorwosidGökçe, İsmail Kürşad/ABI-8128-2020
dc.contributor.authorGokce, Ismail Kursad
dc.contributor.authorOguz, Serife Suna
dc.date.accessioned2024-08-04T20:46:54Z
dc.date.available2024-08-04T20:46:54Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Avoiding hyperoxia with oxygen saturation monitoring is important in the follow-up of very low birth weight (VLBW) infants. Role of oxygen-derived free radicals in the pathogenesis of necrotizing enterocolitis (NEC) has been well defined. However, a great majority of the evidence supporting the role of hyperoxia in NEC development are data from experimental studies and there are very few clinical studies. In this study, the association between NEC and average oxygen saturation (SpO(2)) levels in VLBW infants was researched. Methods: Average SpO(2) values of VLBW infants in the last 24 h were recorded prospectively with pulse oximeter. Average SpO(2) records were continued at least for 10 days starting from the first day after birth. In the follow-up, the average SpO(2) values of the patients who developed NEC and those who did not were compared. Results: A total of 127 VLBW infants were followed up. Thirteen patients developed NEC (Bell's classification >= stage II). No differences were found between the average SpO(2) levels (94.9 and 94.8%) of the patients who developed NEC and those who did not. It was found that average SpO(2) value higher than 93 or 95 was not a risk for NEC development (P = 0.693 and P = 0.771). Conclusions: In this study, no association was found between average SpO(2) values recorded in the first weeks of VLBW infants and NEC.en_US
dc.identifier.doi10.4103/ijpvm.IJPVM_542_18
dc.identifier.issn2008-7802
dc.identifier.issn2008-8213
dc.identifier.pmid31772728en_US
dc.identifier.scopus2-s2.0-85074851584en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.4103/ijpvm.IJPVM_542_18
dc.identifier.urihttps://hdl.handle.net/11616/99026
dc.identifier.volume10en_US
dc.identifier.wosWOS:000564358300005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofInternational Journal of Preventive Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEnterocolitisen_US
dc.subjecthyperoxiaen_US
dc.subjectinfanten_US
dc.subjectnecrotizingen_US
dc.subjectprematureen_US
dc.titleCan High Average Oxygen Saturation be a Risk Factor for Necrotizing Enterocolitis in VLBW Infants?en_US
dc.typeArticleen_US

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