Does cerumen have a risk for transmission of hepatitis B?

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dc.authoridBayindir, Yasar/0000-0003-3930-774X
dc.authoridOZTURAN, ORHAN/0000-0002-6129-8627
dc.authoridDURMAZ, RIZA/0000-0001-6561-778X
dc.authorwosidOZTURAN, ORHAN/E-9610-2012
dc.authorwosidKalcioglu, M. Tayyar/JAC-1515-2023
dc.authorwosidKALCIOGLU, Mahmut Tayyar/I-5884-2013
dc.authorwosidDirekel, Sahin/ABG-1575-2020
dc.authorwosidBayindir, Yasar/T-1523-2017
dc.authorwosidOZTURAN, ORHAN/B-4984-2015
dc.contributor.authorKalcioglu, MT
dc.contributor.authorDurmaz, R
dc.contributor.authorOzturan, O
dc.contributor.authorBayindir, Y
dc.contributor.authorDirekel, S
dc.date.accessioned2024-08-04T20:13:48Z
dc.date.available2024-08-04T20:13:48Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives/Hypothesis: Chronic hepatitis B virus infection is a significant worldwide health problem. It affects 350 to 400 million people. The patients with chronic hepatitis B virus infection have a significant risk for the development of cirrhosis or hepatocellular carcinoma. Full awareness of the mechanisms of transmission can allows susceptible individuals to refrain from this infection. Cerumen has never been studied as a route for hepatitis B transmission. The. of the study was evaluate the importance of cerumen in transmission of hepatitis B virus infection. Study Design: This study was performed on forty patients with confirmed hepatitis B virus infection. Methods: Forty cerumen specimens collected from the patients with hepatitis B virus DNA in their sera were prospectively analyzed for the presence of hepatitis B virus DNA by real-time polymerase chain reaction. Results: Eleven of 40 cerumen specimens (27.5%) were positive for hepatitis B virus DNA, with counts ranging from 4.2 x 10(2) to 4.7 x 10(6) copies per sample. There was positive correlation between hepatitis B virus DNA concentrations of serum and cerumen. Half of hepatitis B e antigen (HBeAg)-positive patients had detectable hepatitis B virus DNA levels (5.7 x 10(2) to 4.7 x 10(6) copies) in cerumen specimens, whereas 12.5% of cerumen specimens from anti-HBe-positive patients had hepatitis B virus DNA levels (4.2 x 10(2) to 7.0 x 10(3) copies). Conclusion: Cerumen can be a potential source of transmission. Therefore, this route should be investigated in further studies for horizontal, nosocomial, and occupational transmission of hepatitis B.en_US
dc.identifier.doi10.1097/00005537-200403000-00035
dc.identifier.endpage580en_US
dc.identifier.issn0023-852X
dc.identifier.issue3en_US
dc.identifier.pmid15091238en_US
dc.identifier.scopus2-s2.0-1642315803en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage577en_US
dc.identifier.urihttps://doi.org/10.1097/00005537-200403000-00035
dc.identifier.urihttps://hdl.handle.net/11616/93865
dc.identifier.volume114en_US
dc.identifier.wosWOS:000220806000031en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofLaryngoscopeen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecthepatitis B virusen_US
dc.subjecttransmissionen_US
dc.subjectcerumenen_US
dc.titleDoes cerumen have a risk for transmission of hepatitis B?en_US
dc.typeArticleen_US

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