Internal mammary artery atherosclerosis in segments removed during coronary artery bypass grafting surgery and C. Pneumoniae infection

dc.authorscopusid6701341322
dc.authorscopusid7006330235
dc.authorscopusid57195695569
dc.authorscopusid6701818265
dc.authorscopusid35616480500
dc.authorscopusid23567847200
dc.authorscopusid35570759500
dc.contributor.authorEge E.
dc.contributor.authorPaç M.
dc.contributor.authorDurmaz R.
dc.contributor.authorBulut Y.
dc.contributor.authorHazar A.
dc.contributor.authorEmmiler M.
dc.contributor.authorAydin N.E.
dc.date.accessioned2024-08-04T20:02:04Z
dc.date.available2024-08-04T20:02:04Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Recent studies suggest the association of atherosclerotic cardiovascular disease with Chlamydia pneumoniae infection. We investigated C. pneumoniae DNA in internal mammarian artery (IMA) (used as a coronary bypass conduit) and its relationship with atherosclerosis. Methods: Sixty-six consecutive patients who underwent coronary artery bypass grafting (CABG) during an eight-month period were included in this study. From all patients, we attempted to obtain surplus segments of harvested IMA grafts. The vessels were examined histopathologically, and presence of C. pneumoniae DNA in IMA grafts was assessed by polymerase chain reaction (PCR). Results: C. pneumoniae DNA was found in 7 (10.6%) of 66 IMA specimens. The light microscopic examinations of IMA segments from the C. pneumonia positive group showed atherosclerotic intimal changes in four of the seven patients. These atherosclerotic changes were type II in three patients and type III in one patient according to the AHA classification. The rest of the IMA segments from 62 patients did not show any discernible atherosclerotic lesion. Conclusion: The IMA graft examination by PCR and histopathology may be helpful in the determination of future graft patency for IMA bypass surgery.en_US
dc.identifier.endpage148en_US
dc.identifier.issn1302-8723
dc.identifier.issue2en_US
dc.identifier.pmid15165950en_US
dc.identifier.scopus2-s2.0-3042533527en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage144en_US
dc.identifier.urihttps://hdl.handle.net/11616/91401
dc.identifier.volume4en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofAnadolu Kardiyoloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAtherosclerosisen_US
dc.subjectChlamydia pneumoniaeen_US
dc.subjectCoronary artery bypassen_US
dc.subjectInternal mammary arteryen_US
dc.subjectPolymerase chain reactionen_US
dc.titleInternal mammary artery atherosclerosis in segments removed during coronary artery bypass grafting surgery and C. Pneumoniae infectionen_US
dc.typeArticleen_US

Dosyalar