The association between intima media thickness, central obesity and diastolic blood pressure in obese and owerweight children: A cross-sectional school-based study

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dc.authoridELKIRAN, OZLEM/0000-0002-6855-0346
dc.authoridİLHAN, NECİP/0000-0001-9997-0418
dc.authoridKAMANLI, AYHAN/0000-0001-5299-7250
dc.authoridYilmaz, Erkan/0000-0001-8962-3199
dc.authoridUstundag, Bilal/0000-0001-6621-2450
dc.authorwosidelkiran, ozlem/ABI-8212-2020
dc.authorwosidÜSTÜNDAĞ, BİLAL/V-9780-2018
dc.authorwosidELKIRAN, OZLEM/AAG-2241-2020
dc.authorwosidİLHAN, NECİP/V-8908-2018
dc.authorwosidKAMANLI, AYHAN/AAC-9523-2022
dc.authorwosidYILMAZ, Erdal/V-9002-2018
dc.authorwosidYilmaz, Erkan/AAB-6178-2020
dc.contributor.authorElkiran, Ozlem
dc.contributor.authorYilmaz, Erdal
dc.contributor.authorKoc, Mustafa
dc.contributor.authorKamanli, Ayhan
dc.contributor.authorUstundag, Bilal
dc.contributor.authorIlhan, Necip
dc.date.accessioned2024-08-04T20:37:34Z
dc.date.available2024-08-04T20:37:34Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To examine relationship between carotid intima-media thickness (IMT) and central obesity, cardiovasculary risk factors, and chronic inflammation markers in overweight and obese schoolchildren in Eastern Turkey. Methods: A cross-sectional school-based survey on 2765 schoolchildren was performed. We collected the clinical data (age, sex, percentage of body fat, and measured systolic blood pressure [BP] and diastolic BP, triglycerides, high-and low-density lipoprotein cholesterol, glucose, insulin, homocysteine and high-sensitivity C-reactive protein) in 67 obese and 24 overweight children. The control group was composed of nonobese children of similar age and sex. Results: Mean systolic and diastolic BP values in the cases of overweight and obese groups were higher than those in the control group cases (p = 0.001). Obese and overweight children demonstrated a significantly thicker intima media as compared with the control group (p = 0.001). Carotid IMT was significantly correlated to the body mass index (r = 0.396, p = 0.001), fat mass percentage (r = 0.257, p = 0.036), waist circumference (r = 0.390, p = 0.001), diastolic BP (r = 0.266, p = 0.030), glucose (r = 0.250, p = 0.042), and high-sensitivity C-reactive protein levels (r = 0.269, p = 0.001) in the obese group. In multiple linear regression analysis, carotid IMT correlated significantly to waist circumference (p = 0.045), and diastolic BP (p = 0.031) in obese group. Conclusions: Obesity is related to cardiovascular risk factors leading to early atherosclerosis in schoolchildren. There is a relationship between atherosclerosis, and central obesity, diastolic BP, and chronic inflammation. Waist circumference measurement is more sensitive than other anthropometric measurements in predicting obesity and associated complications. (c) 2011 Elsevier Ireland Ltd. All rights reserved.en_US
dc.description.sponsorshipFirat Universityen_US
dc.description.sponsorshipThis work was supported by Firat University through its institutional facilities. The authors of this manuscript have certified that they comply with the Principles of Ethical Publishing in the International Journal of Cardiology.en_US
dc.identifier.doi10.1016/j.ijcard.2011.09.080
dc.identifier.endpage532en_US
dc.identifier.issn0167-5273
dc.identifier.issn1874-1754
dc.identifier.issue3en_US
dc.identifier.pmid22014414en_US
dc.identifier.scopus2-s2.0-84877037041en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage528en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijcard.2011.09.080
dc.identifier.urihttps://hdl.handle.net/11616/96043
dc.identifier.volume165en_US
dc.identifier.wosWOS:000318569400033en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChildhood obesityen_US
dc.subjectEarly atherosclerosisen_US
dc.subjectIntima media thicknessen_US
dc.titleThe association between intima media thickness, central obesity and diastolic blood pressure in obese and owerweight children: A cross-sectional school-based studyen_US
dc.typeArticleen_US

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