Overcoming the challenges of drug resistance through combination drug delivery approach

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Tarih

2022

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Elsevier

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Anticancer and antimicrobial drug resistances are the most important problems that decrease the overall success of drug treatment in the clinic. The combination of two or more different kinds of drugs in clinical practice has been generally accepted as a feasible strategy to achieve superior therapeutic efficacy. However, codelivery of drugs in free form may fail due to different solubility, pharmacokinetic behavior, and stability problems. Drug delivery systems, mainly nanoparticulate systems, hold the big potential to achieve this problem. In this chapter, different approaches used in combination therapy to overcome drug resistance are discussed. © 2022 Elsevier Inc. All rights reserved.

Açıklama

Anahtar Kelimeler

combination drug delivery, Drug resistance, nanoparticles

Kaynak

Combination Drug Delivery Approach as an Effective Therapy for Various Diseases

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Scopus Q Değeri

N/A

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