Diffusion-weighted imaging (DWI) of the liver in assessing chronic liver disease: effects of the presence and the degree of ascites on ADC values

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dc.authoridKahraman, Aysegul Sagir/0000-0002-2147-1181
dc.authoridKahraman, Bayram/0000-0002-5447-1110
dc.authoridMARAŞ ÖZDEMİR, ZEYNEP/0000-0003-1085-8978
dc.authoridÖZDEMİR, FATİH/0000-0003-0292-3602
dc.authoridOzdemir, Fatih/0000-0003-0292-3602
dc.authorwosidKahraman, Aysegul Sagir/S-1526-2016
dc.authorwosidKahraman, Bayram/HKM-4798-2023
dc.authorwosidMARAŞ ÖZDEMİR, ZEYNEP/ABI-3319-2020
dc.authorwosidÖZDEMİR, FATİH/HJI-7585-2023
dc.authorwosidOzdemir, Fatih/ABH-2875-2020
dc.contributor.authorKahraman, Aysegul Sagir
dc.contributor.authorKahraman, Bayram
dc.contributor.authorOzdemir, Zeynep Maras
dc.contributor.authorGormeli, Cemile Ayse
dc.contributor.authorOzdemir, Fatih
dc.contributor.authorDogan, Metin
dc.date.accessioned2024-08-04T20:41:37Z
dc.date.available2024-08-04T20:41:37Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: The aim of this study was to determine the correlation between the liver and spleen apparent diffusion coefficient (ADC) values of patients with chronic liver disease and the presence and the degree of ascites. Materials and method: In this retrospective study, we assessed 107 patients with chronic liver disease and 39 control subjects who underwent upper abdominal MR imaging including echo-planar diffusion-weighted imaging (DWI). Among the 107 cirrhotic patients, 56 were classified as group 1, 25 as group 2, and 26 as group 3 according to the absence, the presence of minimal, and the presence of massive ascites, respectively. The scores of model for end-stage liver disease (MELD) were matched between groups as the standard reference. The liver ADC, spleen ADC, and normalized liver ADC values were compared between the control group and patients' groups. Results: Patients with massive ascites had significantly higher MELD score compared with the other groups. The MELD score was also significantly higher in patient groups than in control group. The liver and normalized liver ADCs of patients' groups were significantly lower than that of the control group. With some overlap among groups, the measured ADC values decreased as the amount of the ascites increased, and these relationships were statistically significant. Furthermore, compared to control group, patients with massive ascites had significantly higher spleen ADCs. Conclusion: Our results indicate that the ADC value of the liver and spleen correlates with the presence and the degree of ascites in patients with chronic liver disease, and merits further study.en_US
dc.identifier.doi10.1007/s00261-015-0613-7
dc.identifier.endpage62en_US
dc.identifier.issn2366-004X
dc.identifier.issn2366-0058
dc.identifier.issue1en_US
dc.identifier.pmid26830612en_US
dc.identifier.scopus2-s2.0-84962173336en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage56en_US
dc.identifier.urihttps://doi.org/10.1007/s00261-015-0613-7
dc.identifier.urihttps://hdl.handle.net/11616/97243
dc.identifier.volume41en_US
dc.identifier.wosWOS:000374109400009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAbdominal Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMagnetic resonance imagingen_US
dc.subjectDiffusion-weighted MRIen_US
dc.subjectADC measurementsen_US
dc.subjectChronic liver diseaseen_US
dc.subjectAscitesen_US
dc.titleDiffusion-weighted imaging (DWI) of the liver in assessing chronic liver disease: effects of the presence and the degree of ascites on ADC valuesen_US
dc.typeArticleen_US

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