Genotoxic effects of banding procedure with different orthodontic cements on human oral mucosa cells

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dc.authoridYuksel, Sengul/0000-0002-7190-431X
dc.authoridKURTOĞLU, Elçin Latife/0000-0002-8375-8399
dc.authorwosidASLAN, Elçin Latife/A-3923-2017
dc.authorwosidYuksel, Sengul/ABI-2182-2020
dc.authorwosidKURTOĞLU, Elçin Latife/AAQ-6842-2020
dc.contributor.authorOzturk, Firat
dc.contributor.authorYuksel, Sengul
dc.contributor.authorToy, Ebubekir
dc.contributor.authorKurtoglu, Elcin Latife
dc.contributor.authorKucuk, Eyup Burak
dc.date.accessioned2024-08-04T20:36:16Z
dc.date.available2024-08-04T20:36:16Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: To assess the genotoxic and cytotoxic effects of banding procedure with 5 different orthodontic cements on human oral buccal epithelium cells. Materials and methods: Fifty healthy volunteers (mean age: 14.54 +/- 2.37 years) were randomly divided into 5 groups of 10. Preformed stainless steel molar bands (3M Unitek) were cemented to the upper and lower first molar teeth with 5 different orthodontic cements (Durelon, GC Fuji Ortho Band LC Paste Pak, Meron, Ultra Band Lok, and 3M Unitek Multi Cure) in each group. Genotoxic effects of the banding procedure for a 1-month period were evaluated using the micronucleus test (MNT). To monitor cytotoxic effects, binucleated cells (BNs), karyolysis (KL), and karyorrhexis (KR) were also evaluated in this setting. Results: Analysis of micronuclei in buccal epithelial cells revealed a significant increase in chromosomal damage in all groups (P < 0.01). Significant differences were found in the number of BNs in the groups receiving treatment with Meron, Ultra Band Lok, Durelon, and 3M Multi Cure (P < 0.01). Banding with GC Fuji and Durelon significantly elevated KL frequencies (P <0.05). Durelon had a significant effect on KR (P < 0.01). Conclusion: Band cementation with conventional glass ionomer cement (Meron) showed the least genotoxic effects. The highest cytotoxic effects on human oral buccal epithelium cells were found in the polycarboxylate cement (Durelon) group.en_US
dc.identifier.doi10.3906/sag-1201-60
dc.identifier.endpage1165en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.scopus2-s2.0-84871248201en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1157en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1201-60
dc.identifier.urihttps://hdl.handle.net/11616/95889
dc.identifier.volume42en_US
dc.identifier.wosWOS:000312424300002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiocompatibilityen_US
dc.subjectcytotoxicityen_US
dc.subjectgenotoxicityen_US
dc.subjectmicronucleus testen_US
dc.titleGenotoxic effects of banding procedure with different orthodontic cements on human oral mucosa cellsen_US
dc.typeArticleen_US

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