The roles of thiol oxidoreductases in yeast replicative aging

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dc.contributor.authorHacıoğlu, Elise
dc.contributor.authorEsmer, Işıl
dc.contributor.authorFomenko, Dmitri E.
dc.contributor.authorGladyshev, Vadim N.
dc.contributor.authorKoç, Ahmet
dc.date.accessioned2017-06-11T11:51:37Z
dc.date.available2017-06-11T11:51:37Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.descriptionMechanisms of Ageing and Development 131 (2010) 692–699.en_US
dc.description.abstractThiol-based redox reactions are involved in the regulation of a variety of biological functions, such as protection against oxidative stress, signal transduction and protein folding. Some proteins involved in redox regulation have been shown to modulate life span in organisms from yeast to mammals. To assess the role of thiol oxidoreductases in aging on a genome-wide scale, we analyzed the replicative life span of yeast cells lacking known and candidate thiol oxidoreductases. The data suggest the role of several pathways in controlling yeast replicative life span, including thioredoxin reduction, protein folding and degradation, peroxide reduction, PIP3 signaling, and ATP synthesis.en_US
dc.identifier.citationElise, H., ESMER DEMİRCİ, I., Dmitri E, F., Vadim N, G., & KOÇ, A. (2010). The Roles Of Thiol Oxidoreductases İn Yeast Replicative Aging. Mechanisms Of Ageing And Development, 131(11-12), 692–699.en_US
dc.identifier.doi10.1016/j.mad.2010.09.006en_US
dc.identifier.endpage699en_US
dc.identifier.issue11-12en_US
dc.identifier.startpage692en_US
dc.identifier.urihttp://linkinghub.elsevier.com/retrieve/pii/S0047637410001776
dc.identifier.urihttps://hdl.handle.net/11616/7082
dc.identifier.volume131en_US
dc.language.isoenen_US
dc.publisherMechanisms of Ageing and Developmenten_US
dc.relation.ispartofMechanisms of Ageing and Developmenten_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOxidoreductaseen_US
dc.subjectAntioxidanten_US
dc.subjectOxidationen_US
dc.subjectAgingen_US
dc.subjectLife spanen_US
dc.titleThe roles of thiol oxidoreductases in yeast replicative agingen_US
dc.typeArticleen_US

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