THE ALBUMIN-GLOBULIN RATIO PREDICTING MORTALITY IN GASTRIC CARCINOMA

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dc.authoridbilgic, yılmaz/0000-0002-2169-5548
dc.authoridOzcan, Mete/0000-0002-5551-4880
dc.authoridBozdag, Ahmet/0000-0003-1973-2511
dc.authoridDurak, Serdar/0000-0002-8175-9611
dc.authoridaksoy, asude/0000-0002-5609-9658
dc.authorwosidbilgic, yılmaz/ABI-6432-2020
dc.authorwosidOzcan, Mete/V-8758-2018
dc.authorwosidBozdag, Ahmet/C-6418-2018
dc.contributor.authorAksoy, Asude
dc.contributor.authorDurak, Serdar
dc.contributor.authorOzturk, Turkan
dc.contributor.authorAvci, Nilufer
dc.contributor.authorCirak, Yalcin
dc.contributor.authorDeger, Ayse Nur
dc.contributor.authorBilgic, Yilmaz
dc.date.accessioned2024-08-04T20:42:44Z
dc.date.available2024-08-04T20:42:44Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: The potential effects of serum albumin and albumin-globulin rate on survival were investigated in patients with gastric carcinoma. Materials and methods: The biochemical values of 204 patients under chemotherapy evaluation were obtained retrospectively from archive data. Albumin-globulin ratio values were calculated using albumin/total protein-albumin formula. The values of albumin-globulin ratio and albumin were categorized as 3 groups using receiver operating characteristic analysis and a descending order. Results: The calculated cut-off value for albumin-globulin ratio was 1.14: 34.4-79.7 by receiver operating characteristic. The median survival was 20.7 months (15.9-25.5), 20.1 months (15.1-25.1), 16 months (11.8-20.1), respectively in 1st, 2nd, 3rd groups for albumin-globulin ratio (p=0.46). The median overall survival was 18.3 months (123-24.2), 21.6 months (16.8-26.3), 18.01 months (13.5-22.4) in 1st, 2nd, 3rd groups for albumin, respectively (p=0.52). There were no statistical significant differences by Kaplan-Meier method for albumin-globulin ratio, albumin p>0.05. The effects of clinicopathological and biochemical characteristics on mortality were assessed by Cox-proportional hazard regression analysis. The independent predictors of mortality were observed high grade, the presence of perineural invasion of the tumor, high nodal involvement (p:0.01, p:0.001, p:0.01), respectively. Conclusion: Albumin-globulin ratio and albumin values alone may not be useful parameters to predict mortality and survival in patients with gastric carcinoma.en_US
dc.identifier.doi10.19193/0393-6384_2016_3_78
dc.identifier.endpage712en_US
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84994248944en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage707en_US
dc.identifier.urihttps://doi.org/10.19193/0393-6384_2016_3_78
dc.identifier.urihttps://hdl.handle.net/11616/97564
dc.identifier.volume32en_US
dc.identifier.wosWOS:000376693400007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlbumin-globulin ratioen_US
dc.subjectalbuminen_US
dc.subjectgastric carcinomaen_US
dc.subjectpredictiveen_US
dc.subjectsurvivalen_US
dc.titleTHE ALBUMIN-GLOBULIN RATIO PREDICTING MORTALITY IN GASTRIC CARCINOMAen_US
dc.typeArticleen_US

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