Stenotrophomonas maltophilia outbreak with a commercial blood gas injector as the culprit and interventions for source and prevention: A possible passage between patient and ECMO water heater device
Küçük Resim Yok
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Mosby-Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Despite low virulence of Stenotrophomonas maltophilia, it represents one of the leading drug -resistant bacteria. We report a large outbreak of S. maltophilia infection associated with an unexpected source, which turned out to be a commercial needleless blood gas injector. Methods: Over a period from January 1 to December10, 2021, 113 patients were identified to have S. malto-philia infection as documented by positive cultures from the clinical samples, extracorporeal membrane oxy-genation (ECMO) water heater devices and commercial needleless blood gas injectors. Results: Sixty-seven isolates (59 clinical, 4 ECMO, 4 blood gas injectors) were sent for molecular analysis. Both arbitrarily primed polymerase chain reaction and pulsed -field gel electrophoresis analyses showed 12 distinct genotypes. Of 67 isolates, 58 were clonally related (86.6%), with 52 indistinguishable strains from 4 blood gas needleless injectors, 46 patients' samples (78%), and 2 ECMO samples (50%). Two ECMO samples and 1 clinical sample were clonally identical. Conclusions: In the event that eradication of infections would not be possible despite taking all environmen-tal disinfection measures including the ECMO devices, unexpected sources, such as a commercial needleless blood gas injector, should not be omitted from the list for surveillance. In addition, obtaining surveillance cul-tures of ECMO water reservoirs should be placed in the routine clinical practice. & COPY; 2022 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
Açıklama
Anahtar Kelimeler
Hospital outbreak, ECMO water heater, Injectors
Kaynak
American Journal of Infection Control
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
51
Sayı
5
