The effects of orchiopexy on serum anti-Mullerian hormone levels in unilateral cryptorchid infants

Basit Öğe Kaydı
dc.authoridDemircan, Mehmet/0000-0002-4022-1276
dc.authoridMutus, Huseyin Murat/0000-0002-0059-1336;
dc.authorwosidDemircan, Mehmet/B-1904-2008
dc.authorwosidMutus, Huseyin Murat/AAA-2357-2020
dc.authorwosidDemircan, Mehmet/AAW-7162-2020
dc.contributor.authorDemircan, M
dc.contributor.authorAkinci, A
dc.contributor.authorMutus, M
dc.date.accessioned2024-08-04T20:15:21Z
dc.date.available2024-08-04T20:15:21Z
dc.date.issued2006
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground/Purpose: In males, serum anti-Mullerian hormone (AMH) reflects Sertoli cell function and provides an estimate of seminiferous tubular integrity. It has been suggested that comparison of AMH levels before and after surgery could be useful to determine effectiveness of the treatment. In this study, we determined the serum AMH levels in infants with unilateral cryptorchidism before and after orchiopexy procedure and compared these data with the AMH values in age-matched controls. Methods: The study population was 20 cryptorchid children with unilateral palpable testes who underwent orchiopexy as a cryptorchid group, and 20 healthy children who underwent circumcision as a control group. All children are 12 months of age. Serum AMH levels were measured at just before surgery (at 12 month old) and 6 months after surgery (at 18 month old). Results and Conclusions: All undescended testes were found to be normal in size and in the superficial inguinal pouch or subcutaneous region of the groin at surgery. With regard to the preoperative serum AMH levels, there was a significant difference between the cryptorchid and the control groups (40.04 +/- 4.97 ng/ml versus 53.46 +/- 7.51 ng/ml) (P < 0.05). Similarly, the postoperative serum AMH levels were lower in cryptorchid children than in controls (39.27 +/- 4.58 ng/ml versus 52.79 +/- 6.27 ng/ml) (P < 0.05). In cryptorchid children, serum AMH levels measured at 6 months after orchiopexy were similar with preoperative basal levels (40.04 +/- 4.97 ng/ml versus 39.27 +/- 4.58 ng/ml) (P > 0.05). AMH levels in children with unilateral palpable undescended testes remain unchanged 6 months after orchiopexy performed at 1 year of age. This is the first report in literature regarding the effect of orchiopexy on the serum AMH levels.en_US
dc.identifier.doi10.1007/s00383-006-1646-3
dc.identifier.endpage273en_US
dc.identifier.issn0179-0358
dc.identifier.issn1437-9813
dc.identifier.issue3en_US
dc.identifier.pmid16463168en_US
dc.identifier.scopus2-s2.0-33644979343en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage271en_US
dc.identifier.urihttps://doi.org/10.1007/s00383-006-1646-3
dc.identifier.urihttps://hdl.handle.net/11616/94313
dc.identifier.volume22en_US
dc.identifier.wosWOS:000236032700016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofPediatric Surgery Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectanti-Mullerian hormone (AMH)en_US
dc.subjectMullerian inhibiting substanceen_US
dc.subjectundescended testisen_US
dc.subjectcryptorchidismen_US
dc.subjectorchiopexyen_US
dc.titleThe effects of orchiopexy on serum anti-Mullerian hormone levels in unilateral cryptorchid infantsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu