Enterotoxigenic Bacteroides fragilis as a factor in diarrhea
Küçük Resim Yok
Tarih
2002
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The etiology of almost half of the diarrheal diseases has not been cleared yet, in spite of modern diagnostic methods. Bacteroides fragilis strains which secrete an enterotoxin are termed as enterotoxigenic B.fragilis (ETBF). These strains are associated with diarrheal diseases in children above 1 year of age and in adults. B. fragilis toxin (BFT) stimulates intestinal secretion and in-vitro cytotoxic response in HT29/C1 cells. Recent studies suggest that BFT is related to inflammatory bowel disease and colon cancer by triggering nuclear activation with potential oncogene expression. In this review, the molecular pathogenesis, epidemiology and laboratory diagnosis of ETBF have been reviewed to focus on ETBF as a diarrheal agent.
Açıklama
Anahtar Kelimeler
enterotoxin, bacterial infection, Bacteroides fragilis, biosynthesis, colon tumor, diarrhea, enteritis, human, microbiology, pathogenicity, review, Bacteroides fragilis, Bacteroides Infections, Colonic Neoplasms, Diarrhea, Enterotoxins, Humans, Inflammatory Bowel Diseases
Kaynak
Mikrobiyoloji bülteni
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
36
Sayı
1
